Literature DB >> 2884812

Depressed melatonin secretion in patients with nightmares due to beta-adrenoceptor blocking drugs.

K Brismar, L Mogensen, L Wetterberg.   

Abstract

Nocturnal urinary melatonin excretion was evaluated in six patients with nightmares and hallucinations during treatment with beta-adrenoceptor blocking agents, and compared to six control patients with similar diagnoses and treatment but without such symptoms from the central nervous system (CNS). Nightly melatonin excretion was lower in all cases with nightly CNS-symptoms than in the control patients. The results also suggest drug differences and dose dependency. It is concluded that in predisposed patients CNS side-effects induced by beta-adrenoceptor antagonists are related to depressed nightly melatonin secretion.

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Year:  1987        PMID： 2884812     DOI： 10.1111/j.0954-6820.1987.tb01260.x

Source DB:  PubMed          Journal:  Acta Med Scand        ISSN： 0001-6101


  15 in total

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5.  Influence of chronic beta-adrenoreceptor blocker treatment on melatonin secretion and sleep quality in patients with essential hypertension.

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6.  Melatonin reduces tachycardia in postural tachycardia syndrome: a randomized, crossover trial.

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Review 7.  Neurobiology of circadian systems.

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9.  Night-time exogenous melatonin administration may be a beneficial treatment for sleeping disorders in beta blocker patients.

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10.  Metoprolol-induced visual hallucinations: a case series.

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