| Literature DB >> 28848012 |
Gholam Reza Shokoohi1, Hamid Badali2, Hossein Mirhendi3, Saham Ansari4, Ali Rezaei-Matehkolaei5, Bahram Ahmadi6, Afsane Vaezi2,7, Mohamed Mahdi Alshahni8, Koichi Makimura8.
Abstract
The in vitro activities of novel azoles compared to those of five antifungal drugs against clinical (n = 28) and environmental (n = 102) isolates of black mold and melanized yeast were determined. Luliconazole and lanoconazole had the lowest geometric mean MICs, followed by efinaconazole, against tested isolates compared to the other drugs. Therefore, it appears that these new imidazole and triazole drugs are promising candidates for the treatment of infections due to melanized fungi and their relatives.Entities:
Keywords: MIC; efinaconazole; in vitro; lanoconazole; luliconazole; melanized fungi
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Year: 2017 PMID: 28848012 PMCID: PMC5655049 DOI: 10.1128/AAC.00635-17
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191