Yan-Yan Zhang1, Dian-Can Wang1, Jia-Zeng Su1, Ling-Fei Jia1,2, Xin Peng1, Guang-Yan Yu1. 1. Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China. 2. Central Laboratory, Peking University School and Hospital of Stomatology, Beijing, China.
Abstract
BACKGROUND: The clinicopathological features and outcomes of squamous cell carcinoma (SCC) of the tongue in patients of different age groups remain debatable. METHODS: Medical records of 457 patients with tongue SCC were reviewed, grouped by age, followed up, and compared. RESULTS: Sex and TNM stage showed no intergroup differences. Tongue SCC in patients ≤30 years had the most advanced TNM classification and greatest proportion of poorly differentiation tumors. Both disease-free survival (DFS) and disease-specific survival (DSS) showed no statistically significant difference between the youngest and the oldest groups (P = .605 and P = .520). However, there was a tendency of higher death rate caused by recurrence or metastasis in the youngest group compared with the others (91.7% vs 75.4% and 77.4%). CONCLUSION: Young patients had a tendency of higher death rate caused by recurrence or metastasis than middle-age and older patients; therefore, a larger case sample is needed for further confirmation.
BACKGROUND: The clinicopathological features and outcomes of squamous cell carcinoma (SCC) of the tongue in patients of different age groups remain debatable. METHODS: Medical records of 457 patients with tongue SCC were reviewed, grouped by age, followed up, and compared. RESULTS: Sex and TNM stage showed no intergroup differences. Tongue SCC in patients ≤30 years had the most advanced TNM classification and greatest proportion of poorly differentiation tumors. Both disease-free survival (DFS) and disease-specific survival (DSS) showed no statistically significant difference between the youngest and the oldest groups (P = .605 and P = .520). However, there was a tendency of higher death rate caused by recurrence or metastasis in the youngest group compared with the others (91.7% vs 75.4% and 77.4%). CONCLUSION: Young patients had a tendency of higher death rate caused by recurrence or metastasis than middle-age and older patients; therefore, a larger case sample is needed for further confirmation.
Authors: Melina Windon; Carole Fakhry; Lisa Rooper; Patrick Ha; David Schoppy; Brett Miles; Wayne Koch; Peter Vosler; David Eisele; Gypsyamber D'Souza Journal: Otolaryngol Head Neck Surg Date: 2020-06-23 Impact factor: 3.497
Authors: Sophie Deneuve; Joanne Guerlain; Agnès Dupret-Bories; Claire Majoufre; Pierre Philouze; Philippe Ceruse; Marion Perreard; Nicolas Sigaud; Béatrix Barry; Pierre Ransy; Philippe Schultz; Olivier Malard; Sylvain Morinière; Anne Chatellier; Erwan De Monès; Mireille Folia; François Virard; Béatrice Fervers Journal: Eur Arch Otorhinolaryngol Date: 2021-04-20 Impact factor: 2.503
Authors: David S Lee; Ricardo J Ramirez; Jake J Lee; Carla V Valenzuela; Jose P Zevallos; Angela L Mazul; Sidharth V Puram; Michelle M Doering; Patrik Pipkorn; Ryan S Jackson Journal: Laryngoscope Date: 2020-12-02 Impact factor: 2.970
Authors: A Marra; M Violati; F Broggio; C Codecà; M Blasi; A Luciani; S Zonato; D Rabbiosi; L Moneghini; A Saibene; A Maccari; G Felisati; D Ferrari Journal: Acta Otorhinolaryngol Ital Date: 2019-04 Impact factor: 2.124