Literature DB >> 2884293

Albumin microspheres for intra-articular drug delivery: investigation of their retention in normal and arthritic knee joints of rabbits.

J H Ratcliffe, I M Hunneyball, C G Wilson, A Smith, S S Davis.   

Abstract

The retention of 131I-labelled albumin microspheres and microsphere-entrapped [131I]rose bengal was investigated in normal and experimentally arthritic knee joints of rabbits. Albumin microspheres were cleared slowly from the joint cavity and no significant difference was observed between normal and inflamed joints. Entrapment of rose bengal within albumin microspheres was found to delay the clearance of the drug from the joint when compared with a solution of rose bengal. In addition, the retention time for entrapped rose bengal was dependent on the degree of inflammation present.

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Year:  1987        PMID： 2884293     DOI： 10.1111/j.2042-7158.1987.tb06268.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN： 0022-3573            Impact factor:   3.765


  9 in total

1.  Synthesis and characterization of silk fibroin microparticles for intra-articular drug delivery.

Authors:  Timothy K Mwangi; Robby D Bowles; David M Tainter; Richard D Bell; David L Kaplan; Lori A Setton
Journal:  Int J Pharm       Date:  2015-02-24       Impact factor: 5.875

2.  Size-dependency of DL-lactide/glycolide copolymer particulates for intra-articular delivery system on phagocytosis in rat synovium.

Authors:  Eijiro Horisawa; Katsuaki Kubota; Izumi Tuboi; Keiichi Sato; Hiromitsu Yamamoto; Hirofumi Takeuchi; Yoshiaki Kawashima
Journal:  Pharm Res       Date:  2002-02       Impact factor: 4.200

3.  Prolonged anti-inflammatory action of DL-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit.

Authors:  Eijiro Horisawa; Tsuyoshi Hirota; Satoko Kawazoe; Jun Yamada; Hiromitsu Yamamoto; Hirofumi Takeuchi; Yoshiaki Kawashima
Journal:  Pharm Res       Date:  2002-04       Impact factor: 4.200

Review 4.  Evaluating intra-articular drug delivery for the treatment of osteoarthritis in a rat model.

Authors:  Kyle D Allen; Samuel B Adams; Lori A Setton
Journal:  Tissue Eng Part B Rev       Date:  2010-02       Impact factor: 6.389

5.  Particles for Local Delivery of Proteins Using Intra-Articular Route.

Authors:  Khosrow Khodabandehlou; Shaomin Tian; James C Luft; Saad A Khan; Joseph M DeSimone
Journal:  Adv Healthc Mater       Date:  2016-02-02       Impact factor: 9.933

6.  Gastroretentive microballoons of metformin: Formulation development and characterization.

Authors:  Akash Yadav; Dinesh Kumar Jain
Journal:  J Adv Pharm Technol Res       Date:  2011-01

7.  The TAT Protein Transduction Domain as an Intra-Articular Drug Delivery Technology.

Authors:  Sarah E Mailhiot; Matthew A Thompson; Akiko E Eguchi; Sabrina E Dinkel; Martin K Lotz; Steven F Dowdy; Ronald K June
Journal:  Cartilage       Date:  2020-09-19       Impact factor: 3.117

8.  Intra-articular delivery of tetramethylpyrazine microspheres with enhanced articular cavity retention for treating osteoarthritis.

Authors:  Xiuping Zhang; Yang Shi; Zhiyue Zhang; Zhenlei Yang; Guihua Huang
Journal:  Asian J Pharm Sci       Date:  2018-01-04       Impact factor: 6.598

9.  Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice.

Authors:  Nicoleta Butoescu; Christian A Seemayer; Gaby Palmer; Pierre-André Guerne; Cem Gabay; Eric Doelker; Olivier Jordan
Journal:  Arthritis Res Ther       Date:  2009-05-19       Impact factor: 5.156
  9 in total

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