| Literature DB >> 28831518 |
Marc Maegele1,2, Michael Caspers3,4, Herbert Schöchl5.
Abstract
Uncontrolled bleeding is the leading preventable cause of death in patients with multiple injuries. Currently, trauma-induced coagulopathy is seen as an independent disease entity influencing survival. Severely bleeding trauma patients are often treated with classical blood products in predefined ratios (damage control resuscitation). Viscoelasticity-based and target-oriented approaches could possibly be given priority. Viscoelasticity-based diagnostics and therapy enable the qualitative investigation of whole blood and provide therapeutically usable information on initiation, dynamics and sustainability of thrombus formation. Due to the ease of handling and timely results this lends itself as a point-of-care procedure. This article presents the clinical issues with using viscoelastic procedures and current expert recommendations taking the literature into consideration.Entities:
Keywords: Blood coagulation; Fibrinogen; Point-of-care systems; Transfusion; Trauma
Mesh:
Substances:
Year: 2017 PMID: 28831518 DOI: 10.1007/s00113-017-0397-z
Source DB: PubMed Journal: Unfallchirurg ISSN: 0177-5537 Impact factor: 1.000