| Literature DB >> 28827697 |
Tzu-Ya Huang1,2, Chih-Kuang Liang1,3,4,5, Hsiu-Chu Shen1,3, Hon-I Chen2, Mei-Chen Liao1, Ming-Yueh Chou6,7, Yu-Te Lin1,3, Liang-Kung Chen8,9.
Abstract
The impact of dynapenia on the complexity of care for residents of long-term care facilities (LTCF) remains unclear. The present study evaluated associations between dynapenia, care problems and care complexity in 504 residents of Veterans Care Homes (VCHs) in Taiwan. Subjects with dynapenia, defined as low muscle strength (handgrip strength <26 kg), were older adults with lower body mass index (BMI), slow gait speed, and higher numbers of Resident Assessment Protocol (RAP) triggers. After adjusting for age, education, BMI, and Charlson's comorbidity index (CCI), only age, education, BMI and gait speed were independently associated with higher numbers of RAP triggers, but not dynapenia or handgrip strength (kg). Dividing subjects into groups based on quartiles of gait speed, those with gait speed ≤0.803 m/s were significantly associated with higher complexity of care needs (defined as ≥4 RAP triggers) compared to the reference group (gait speed >1 m/s). Significantly slow gait speed was associated with RAP triggers, including cognitive loss, poor communication ability, rehabilitation needs, urinary incontinence, depressed mood, falls, pressure ulcers, and use of psychotropic drugs. In conclusion, slow gait speed rather than dynapenia is a simple indicator for higher complexity of care needs of older male LTCF residents.Entities:
Mesh:
Year: 2017 PMID: 28827697 PMCID: PMC5566363 DOI: 10.1038/s41598-017-08791-4
Source DB: PubMed Journal: Sci Rep ISSN: 2045-2322 Impact factor: 4.379
Subjects’ demographic and anthropometric characteristics with or without dynapenia*.
| Total N = 504% or mean ± SD | Dynapenia | Non-Dynapenia | P value | |
|---|---|---|---|---|
| N = 330% or mean ± SD | N = 174% or mean ± SD | |||
| Age† | 82.6 ± 4.7 | 82.9 ± 4.9 | 82.0 ± 4.3 | <0.001 |
| Educational level‡ | 0.922 | |||
| No formal education | 268 (53.2%) | 176 (53.3%) | 92 (52.9%) | |
| Higher than Primary school | 236 (46.8%) | 154 (46.7%) | 82 (47.1%) | |
| Body mass index (kg/m2)† | 23.3 ± 3.4 | 23.1 ± 3.5 | 23.8 ± 3.2 | 0.042 |
| Charlson’s comorbidity index † | 0.64 ± 0.83 | 0.69 ± 0.87 | 0.55 ± 0.75 | 0.073 |
| Gait speed (m/s)† | 0.794 ± 0.324 | 0.729 ± 0.314 | 0.916 ± 0.307 | <0.001 |
| Handgrip stretch (kg)† | 22.5 ± 6.8 | 18.7 ± 4.6 | 29.8 ± 3.4 | <0.001 |
| Sum of RAP triggers† | 4.3 ± 2.1 | 4.5 ± 2.3 | 3.8 ± 1.7 | <0.001 |
Values presented as †mean ± standard deviation; ‡number (%).
*Defined by EWGSOP criteria (European Working Group on Sarcopenia for Older People, 2010[17]).
DLMS: Based on Handgrip strength <26 kg.
RAP: Resident Assessment Protocol.
Multiple linear regression analysis of risk factors for higher complexity of care needs* according to RAP triggers.
| Model 1 | Model 2 | Model 3 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| β (standardized co- efficient) | t | p | β (standardized co- efficient) | t | p | β (standardized co- efficient) | t | p | |
| Age | 0.215 | 4.826 | <0.001 | 0.146 | 3.277 | 0.001 | 0.144 | 3.229 | 0.001 |
| Education(Yes) | −0.094 | −2.140 | 0.033 | −0.089 | −2.102 | 0.036 | −0.087 | −2.066 | 0.039 |
| CCI | 0.077 | 1.759 | 0.079 | 0.038 | 0.896 | 0.371 | 0.038 | 0.878 | 0.380 |
| BMI | −0.092 | −2.093 | 0.037 | −0.100 | −2.359 | 0.019 | −0.098 | −2.301 | 0.022 |
| Dynapenia(Yes) | 0.124 | 2.819 | 0.005 | −0.060 | 1.380 | 0.168 | |||
| Gait speed(m/s) | — | — | — | −0.270 | −5.958 | <0.001 | −0.260 | −5.505 | <0.001 |
| Handgrip strength(kg) | — | — | — | −0.070 | 1.525 | 0.128 | |||
*Higher complexity of care needs defined as ≥4 RAP triggers.
CCI: Charlson’s comorbidity index; BMI: body mass index; RAP: Resident assessment protocol.
Dynapenia: Based on Handgrip strength <26kg.
Model 1: Adjusted for Age, Educational level, CCI, BMI, and Dynapenia, R2 = 0.088.
Model 2: Adjusted for Age, Educational level, CCI, BMI, Dynapenia and Gait speed, R2 = 0.160.
Model 3: Adjusted for Age, Educational level, CCI, BMI, Handgrip strength (kg) and Gait speed, R2 = 0.149.
Multivariate logistic regression for independent associations between gait speed quartiles and higher complexity of care needs.
| Gait Speed Group | Unadjusted | Adjusted | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | |
| Q 1 | Reference | Reference | Reference | Reference | ||
| Q 2 | 1.763 | 1.047 – 2.969 | 0.033 | 1.627 | 0.946–2.800 | 0.079 |
| Q 3 | 2.696 | 1.545–4.705 | <0.001 | 2.482 | 1.389–4.435 | 0.002 |
| Q 4 | 4.715 | 2.643–8.411 | <0.001 | 4.224 | 2.235–7.981 | <0.001 |
Adjusting for age, education, BMI, CCI, Dynapenia.
CCI: Charlson’s comorbidity index; BMI: body mass index; RAP: Resident assessment protocol.
Dynapenia: Based on Handgrip strength <26 kg.
Higher complexity of care needs: defined as ≥4 RAP triggers.
Q 1: gait speed >1.000.
Q 2: gait speed 0.804~1.000.
Q 3: gait speed 0.546~0.803.
Q 4: gait speed <0.546.
Comparisons of mean gait speed between residents with individual RAP triggers.
| Gait speed (meter/s) | |||||
|---|---|---|---|---|---|
| RAP trigger (+) | RAP trigger (−) |
| |||
| N | Mean ± SD | N | Mean ± SD | ||
| 1. Delirium | 32 | 0.693 ± 0.313 | 472 | 0.799 ± 0.323 | 0.073 |
| 2. Cognitive loss | 113 | 0.695 ± 0.302 | 391 | 0.822 ± 0.325 | <0.001 |
| 3. Visual function | 195 | 0.772 ± 0.336 | 309 | 0.810 ± 0.315 | 0.228 |
| 4. Communication | 185 | 0.709 ± 0.297 | 319 | 0.843 ± 0.329 | <0.001 |
| 5. Rehabilitation needs | 188 | 0.751 ± 0.356 | 316 | 0.819 ± 0.301 | 0.028 |
| 6. Urinary incontinence | 42 | 0.569 ± 0.311 | 462 | 0.814 ± 0.318 | <0.001 |
| 7. Psychosocial well-being | 332 | 0.777 ± 0.314 | 172 | 0.825 ± 0.341 | 0.116 |
| 8. Depressed mood | 106 | 0.686 ± 0.323 | 398 | 0.822 ± 0.318 | <0.001 |
| 9. Behavioral symptoms | 2 | 0.875 ± 0.177 | 502 | 0.793 ± 0.324 | 0.722 |
| 10. Activities | 228 | 0.773 ± 0.348 | 276 | 0.810 ± 0.302 | 0.206 |
| 11. Falls | 63 | 0.622 ± 0.294 | 441 | 0.818 ± 0.321 | <0.001 |
| 12. Nutritional status | 14 | 0.672 ± 0.333 | 490 | 0.797 ± 0.323 | 0.153 |
| 13. Tube Feeding | 0 | — | 0 | — | — |
| 14. Dehydration | 8 | 0.614 ± 0.356 | 496 | 0.797 ± 0.323 | 0.113 |
| 15. Dental care | 412 | 0.796 ± 0.326 | 92 | 0.784 ± 0.316 | 0.765 |
| 16. Pressure ulcers | 27 | 0.545 ± 0.316 | 477 | 0.808 ± 0.318 | <0.001 |
| 17. Psychotropic drug use | 175 | 0.667 ± 0.299 | 329 | 0.861 ± 0.317 | <0.001 |
| 18. Physical Restraints | 1 | 0.286 | 503 | 0.795 ± 0.323 | 0.117 |
Mean gait speed for total 504 subjects: 0.794 ± 0.324 meter/s.
RAP: Resident assessment protocol.