Literature DB >> 18772470

Sarcopenia =/= dynapenia.

Brian C Clark1, Todd M Manini.   

Abstract

Maximal voluntary force (strength) production declines with age and contributes to physical dependence and mortality. Consequently, a great deal of research has focused on identifying strategies to maintain muscle mass during the aging process and elucidating key molecular pathways of atrophy, with the rationale that the loss of strength is primarily a direct result of the age-associated declines in mass (sarcopenia). However, recent evidence questions this relationship and in this Green Banana article we argue the role of sarcopenia in mediating the age-associated loss of strength (which we will coin as dynapenia) does not deserve the attention it has attracted in both the scientific literature and popular press. Rather, we propose that alternative mechanisms underlie dynapenia (i.e., alterations in contractile properties or neurologic function), and urge that greater attention be paid to these variables in determining their role in dynapenia.

Entities:  

Mesh:

Year:  2008        PMID: 18772470     DOI: 10.1093/gerona/63.8.829

Source DB:  PubMed          Journal:  J Gerontol A Biol Sci Med Sci        ISSN: 1079-5006            Impact factor:   6.053


  251 in total

1.  Sarcopenic indices in community-dwelling older adults.

Authors:  Ericka N Merriwether; Helen H Host; David R Sinacore
Journal:  J Geriatr Phys Ther       Date:  2012 Jul-Sep       Impact factor: 3.381

2.  Plasma heat shock protein 72 as a biomarker of sarcopenia in elderly people.

Authors:  Kishiko Ogawa; Hun-Kyung Kim; Takahiko Shimizu; Sigeaki Abe; Yumi Shiga; Stuart K Calderwood
Journal:  Cell Stress Chaperones       Date:  2011-12-06       Impact factor: 3.667

Review 3.  How to assess functional status: a new muscle quality index.

Authors:  S Barbat-Artigas; Y Rolland; M Zamboni; M Aubertin-Leheudre
Journal:  J Nutr Health Aging       Date:  2012-01       Impact factor: 4.075

4.  Aging, sarcopenia and store-operated calcium entry: a common link?

Authors:  Marco Brotto
Journal:  Cell Cycle       Date:  2011-12-15       Impact factor: 4.534

5.  Designing Phase II B trials in sarcopenia: the best target population.

Authors:  M Pahor; M Cesari
Journal:  J Nutr Health Aging       Date:  2011-08       Impact factor: 4.075

6.  Relationship between long sleep duration and functional capacities in postmenopausal women.

Authors:  Annie Fex; Sébastien Barbat-Artigas; Sophie Dupontgand; Marie-Eve Filion; Antony D Karelis; Mylène Aubertin-Leheudre
Journal:  J Clin Sleep Med       Date:  2012-06-15       Impact factor: 4.062

7.  Skeletal muscle fat infiltration: impact of age, inactivity, and exercise.

Authors:  R L Marcus; O Addison; J P Kidde; L E Dibble; P C Lastayo
Journal:  J Nutr Health Aging       Date:  2010-05       Impact factor: 4.075

Review 8.  Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy.

Authors:  Thomas W Buford; Stephen D Anton; Andrew R Judge; Emanuele Marzetti; Stephanie E Wohlgemuth; Christy S Carter; Christiaan Leeuwenburgh; Marco Pahor; Todd M Manini
Journal:  Ageing Res Rev       Date:  2010-05-14       Impact factor: 10.895

9.  Effects of Vocal Training on Thyroarytenoid Muscle Neuromuscular Junctions and Myofibers in Young and Older Rats.

Authors:  Adrianna C Shembel; Charles Lenell; Sophia Chen; Aaron M Johnson
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2021-01-18       Impact factor: 6.053

10.  Difference in muscle quality over the adult life span and biological correlates in the Baltimore Longitudinal Study of Aging.

Authors:  Ann Zenobia Moore; Giorgio Caturegli; E Jeffrey Metter; Sokratis Makrogiannis; Susan M Resnick; Tamara B Harris; Luigi Ferrucci
Journal:  J Am Geriatr Soc       Date:  2014-01-17       Impact factor: 5.562

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.