Literature DB >> 28820877

Drug development: Locking down metabolism.

William R Bishai1.   

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Year:  2017        PMID： 28820877     DOI： 10.1038/nchembio.2452

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  9 in total

Review 1.  Antibacterial drug discovery in the resistance era.

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Journal:  Nature       Date:  2016-01-21       Impact factor: 49.962

2.  Are essential genes really essential?

Authors:  Michael A D'Elia; Mark P Pereira; Eric D Brown
Journal:  Trends Microbiol       Date:  2009-09-16       Impact factor: 17.079

Review 3.  Targeting bacterial central metabolism for drug development.

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Journal:  Chem Biol       Date:  2014-10-16

Review 4.  Why are membrane targets discovered by phenotypic screens and genome sequencing in Mycobacterium tuberculosis?

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Journal:  Tuberculosis (Edinb)       Date:  2013-09-18       Impact factor: 3.131

Review 5.  Action at a distance: allostery and the development of drugs to target cancer cell metabolism.

Authors:  Byron DeLaBarre; Jonathan Hurov; Giovanni Cianchetta; Stuart Murray; Lenny Dang
Journal:  Chem Biol       Date:  2014-09-18

Review 6.  Using bacterial genomes and essential genes for the development of new antibiotics.

Authors:  Francisco R Fields; Shaun W Lee; Michael J McConnell
Journal:  Biochem Pharmacol       Date:  2016-12-08       Impact factor: 5.858

7.  A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis.

Authors:  Gyanu Lamichhane; Matteo Zignol; Natalie J Blades; Deborah E Geiman; Annette Dougherty; Jacques Grosset; Karl W Broman; William R Bishai
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-29       Impact factor: 11.205

8.  A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.

Authors:  Samantha Wellington; Partha P Nag; Karolina Michalska; Stephen E Johnston; Robert P Jedrzejczak; Virendar K Kaushik; Anne E Clatworthy; Noman Siddiqi; Patrick McCarren; Besnik Bajrami; Natalia I Maltseva; Senya Combs; Stewart L Fisher; Andrzej Joachimiak; Stuart L Schreiber; Deborah T Hung
Journal:  Nat Chem Biol       Date:  2017-07-03       Impact factor: 15.040

9.  Genes required for mycobacterial growth defined by high density mutagenesis.

Authors:  Christopher M Sassetti; Dana H Boyd; Eric J Rubin
Journal:  Mol Microbiol       Date:  2003-04       Impact factor: 3.501
  9 in total
  2 in total

1.  Multi-omics and temporal dynamics profiling reveal disruption of central metabolism in Helicobacter pylori on bismuth treatment.

Authors:  Bingjie Han; Zhen Zhang; Yanxuan Xie; Xuqiao Hu; Haibo Wang; Wei Xia; Yulan Wang; Hongyan Li; Yuchuan Wang; Hongzhe Sun
Journal:  Chem Sci       Date:  2018-07-25       Impact factor: 9.825

2.  A paclitaxel prodrug with bifunctional folate and albumin binding moieties for both passive and active targeted cancer therapy.

Authors:  Lingling Shan; Xin Zhuo; Fuwu Zhang; Yunlu Dai; Guizhi Zhu; Bryant C Yung; Wenpei Fan; Kefeng Zhai; Orit Jacobson; Dale O Kiesewetter; Ying Ma; Guizhen Gao; Xiaoyuan Chen
Journal:  Theranostics       Date:  2018-02-16       Impact factor: 11.556
  2 in total

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