Gema Rebolleda1, Aki Kawasaki2, Victoria de Juan3, Noelia Oblanca1, Francisco Jose Muñoz-Negrete1. 1. Department of Ophthalmology, Hospital Universitario Ramón y Cajal (IRYCIS), Carretera de Colmenar Viejo Km 9.100, 28034, Madrid, Spain. 2. Department of Ophthalmology, Hopital Ophtalmique Jules Gonin, University Lausanne, Lausanne, Switzerland. 3. Department of Ophthalmology, Hospital Universitario Ramón y Cajal (IRYCIS), Carretera de Colmenar Viejo Km 9.100, 28034, Madrid, Spain. victoriadejuanryc@gmail.com.
Abstract
PURPOSE OF REVIEW: Mild papilledema may be difficult to distinguish by clinical observation from pseudopapilledema. An accurate diagnosis is critical to avoid invasive workup and unwarranted treatment. In this review, we focus on the development and subsequent role of optical coherence tomography (OCT) in detecting and differentiating optic nerve head drusen (ONHD) from papilledema and other causes of acquired swelling of the optic disc. RECENT FINDINGS: Newer OCT technologies which permit deeper penetration to improve detection of ONHD were also reviewed. Enhanced depth imaging (EDI) spectral-domain OCT and swept-source (SS) OCT are currently recognized as the most reliable and sensitive tools to diagnose ONHD. OCT devices currently available provide a means to quantify drusen dimensions, to evaluate the integrity of neighboring structures and to monitor axonal and neuronal damage, yielding additional information to better understand the relationship between the morphological features of drusen, and their effects on the structure and function of the optic nerve.
PURPOSE OF REVIEW: Mild papilledema may be difficult to distinguish by clinical observation from pseudopapilledema. An accurate diagnosis is critical to avoid invasive workup and unwarranted treatment. In this review, we focus on the development and subsequent role of optical coherence tomography (OCT) in detecting and differentiating optic nerve head drusen (ONHD) from papilledema and other causes of acquired swelling of the optic disc. RECENT FINDINGS: Newer OCT technologies which permit deeper penetration to improve detection of ONHD were also reviewed. Enhanced depth imaging (EDI) spectral-domain OCT and swept-source (SS) OCT are currently recognized as the most reliable and sensitive tools to diagnose ONHD. OCT devices currently available provide a means to quantify drusen dimensions, to evaluate the integrity of neighboring structures and to monitor axonal and neuronal damage, yielding additional information to better understand the relationship between the morphological features of drusen, and their effects on the structure and function of the optic nerve.
Authors: Mark P Ghassibi; Jason L Chien; Ramiz K Abumasmah; Jeffrey M Liebmann; Robert Ritch; Sung Chul Park Journal: Ophthalmology Date: 2016-11-30 Impact factor: 12.079
Authors: Imran Jivraj; Cesar A Cruz; Maxwell Pistilli; Anita A Kohli; Grant T Liu; Kenneth S Shindler; Robert A Avery; Mona K Garvin; Jui-Kai Wang; Ahmara Ross; Madhura A Tamhankar Journal: J Neuroophthalmol Date: 2021-12-01 Impact factor: 4.415