BACKGROUND AND OBJECTIVE: To compare patterns of choroidal hypoperfusion in white dot syndromes (WDS) using optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: Consecutive patients with WDS were imaged with either the Zeiss AngioPlex OCT Angiography (Carl Zeiss AG, Oberkochen, Germany) or the AngioVue OCT Angiography (Optovue, Fremont, CA) from February to November 2016. Four patients with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), birdshot chorioretinopathy (BCR), presumed ocular histoplasmosis syndrome (POHS), and multiple evanescent white dot syndrome (MEWDS) were selected. This study was approved by the institutional review board at Massachusetts Eye and Ear. RESULTS: Unique patterns of choroidal hypoperfusion were observed. In POHS and MEWDS, areas of choroidal hypoperfusion correlated well with clinically observed pathology, but in APMPPE and BCR, they were more widespread. CONCLUSION: OCTA can identify different patterns of choroidal hypoperfusion in APMPPE, BCR, POHS, and MEWDS, which appears to be a shared feature of WDS. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:638-646.]. Copyright 2017, SLACK Incorporated.
BACKGROUND AND OBJECTIVE: To compare patterns of choroidal hypoperfusion in white dot syndromes (WDS) using optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: Consecutive patients with WDS were imaged with either the Zeiss AngioPlex OCT Angiography (Carl Zeiss AG, Oberkochen, Germany) or the AngioVue OCT Angiography (Optovue, Fremont, CA) from February to November 2016. Four patients with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), birdshot chorioretinopathy (BCR), presumed ocular histoplasmosis syndrome (POHS), and multiple evanescent white dot syndrome (MEWDS) were selected. This study was approved by the institutional review board at Massachusetts Eye and Ear. RESULTS: Unique patterns of choroidal hypoperfusion were observed. In POHS and MEWDS, areas of choroidal hypoperfusion correlated well with clinically observed pathology, but in APMPPE and BCR, they were more widespread. CONCLUSION: OCTA can identify different patterns of choroidal hypoperfusion in APMPPE, BCR, POHS, and MEWDS, which appears to be a shared feature of WDS. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:638-646.]. Copyright 2017, SLACK Incorporated.
Authors: K Matthew McKay; Filippos Vingopoulos; Jay C Wang; Thanos D Papakostas; Rebecca F Silverman; Anna Marmalidou; Inês Lains; Dean Eliott; Demetrios G Vavvas; Leo A Kim; David M Wu; John B Miller Journal: Clin Ophthalmol Date: 2020-06-26
Authors: Vita L S Dingerkus; Marion R Munk; Max P Brinkmann; Florentina J Freiberg; Florian M A Heussen; Stephan Kinzl; Sandra Lortz; Selim Orgül; Matthias Becker Journal: J Ophthalmic Inflamm Infect Date: 2019-05-28
Authors: J Daniel Diaz; Jay C Wang; Patrick Oellers; Inês Lains; Lucia Sobrin; Deeba Husain; Joan W Miller; Demetrios G Vavvas; John B Miller Journal: J Vitreoretin Dis Date: 2018-04-16