Thomas W Clements1, Kelly Vogt2, S Morad Hameed3, Neil Parry2, Andrew W Kirkpatrick1, Sean C Grondin1, Elijah Dixon1, Jessica McKee1, Chad G Ball4. 1. Department of Surgery, University of Calgary, Calgary, Alberta, Canada. 2. Department of Surgery, Western University, London, Ontario, Canada. 3. Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada. 4. Department of Surgery, University of Calgary, Calgary, Alberta, Canada. Electronic address: ball.chad@gmail.com.
Abstract
BACKGROUND: Variance in prehospital time among severely injured blunt trauma patients is dependent upon numerous factors. Effects on subsequent mortality and trauma team activation (TTA) rates are also unclear. The primary aim of this study was to evaluate the relationship between prehospital time and mortality at level I trauma referral centers amongst critically blunt injured patients. MATERIALS AND METHODS: This multiinstitutional study from three geographically distinct level I trauma centers analyzed all severely blunt injured patients (Injury Severity Score [ISS] ≥12). The relationship between prehospital time and survival was evaluated. Secondary outcomes included the association between prehospital time and TTA. Standard statistical methodology was used (P < 0.05 = significance). RESULTS: Between January 1, 2011, and January 1, 2016, 5375 severely blunt injured patients (mean ISS = 25; mean length of stay = 16.3 d) were analyzed (center 1 = 3376; center 2 = 2401; and center 3 = 1104). As prehospital time interval increased, overall mortality decreased (0-30 min = 24.1%; 31-60 min = 14.7%; 61-90 min = 10.3%; 91-120 min = 10.4%; 121-150 min = 10.2%; P < 0.05). This pattern was especially strong for patients with an arrival measurement of hypotension, despite corrections for ISS (P < 0.05). TTA and patient outcomes were extremely variable across intervals and centers (P < 0.05). CONCLUSIONS: A trial of life effect is present for severely blunt injured patients who arrive with vital signs. Despite arrival measurements of hypotension, patients with prolonged prehospital times have a substantially lower risk of subsequent mortality. This concept should contribute to decision-making with regard to TTA.
BACKGROUND: Variance in prehospital time among severely injured blunt traumapatients is dependent upon numerous factors. Effects on subsequent mortality and trauma team activation (TTA) rates are also unclear. The primary aim of this study was to evaluate the relationship between prehospital time and mortality at level I trauma referral centers amongst critically blunt injured patients. MATERIALS AND METHODS: This multiinstitutional study from three geographically distinct level I trauma centers analyzed all severely blunt injured patients (Injury Severity Score [ISS] ≥12). The relationship between prehospital time and survival was evaluated. Secondary outcomes included the association between prehospital time and TTA. Standard statistical methodology was used (P < 0.05 = significance). RESULTS: Between January 1, 2011, and January 1, 2016, 5375 severely blunt injured patients (mean ISS = 25; mean length of stay = 16.3 d) were analyzed (center 1 = 3376; center 2 = 2401; and center 3 = 1104). As prehospital time interval increased, overall mortality decreased (0-30 min = 24.1%; 31-60 min = 14.7%; 61-90 min = 10.3%; 91-120 min = 10.4%; 121-150 min = 10.2%; P < 0.05). This pattern was especially strong for patients with an arrival measurement of hypotension, despite corrections for ISS (P < 0.05). TTA and patient outcomes were extremely variable across intervals and centers (P < 0.05). CONCLUSIONS: A trial of life effect is present for severely blunt injured patients who arrive with vital signs. Despite arrival measurements of hypotension, patients with prolonged prehospital times have a substantially lower risk of subsequent mortality. This concept should contribute to decision-making with regard to TTA.
Authors: Gavin Tansley; Nadine Schuurman; Matthew Bowes; Mete Erdogan; Robert Green; Mark Asbridge; Natalie Yanchar Journal: Can J Surg Date: 2019-04-01 Impact factor: 2.089
Authors: Alexander F Bedard; Lina V Mata; Chelsea Dymond; Fabio Moreira; Julia Dixon; Steven G Schauer; Adit A Ginde; Vikhyat Bebarta; Ernest E Moore; Nee-Kofi Mould-Millman Journal: Int J Emerg Med Date: 2020-12-09
Authors: Yan Yik Lim; Azizi Miskon; Ahmad Mujahid Ahmad Zaidi; Megat Mohamad Hamdan Megat Ahmad; Muhamad Abu Bakar Journal: J Funct Biomater Date: 2022-02-21