Chiyako Oshikata1, Maiko Watanabe2, Akemi Saito3, Masatsugu Ishida4, Seiichi Kobayashi4, Rumi Konuma5, Yoichi Kamata6, Jun Terajima2, Junichi Cho7, Masaru Yanai4, Naomi Tsurikisawa1. 1. 1National Hospital Organization Saitama National Hospital,Department of Respirology,Wako,Saitama,Japan. 2. 3Division of Microbiology,National Institute of Health Science,Setagaya-ku,Tokyo,Japan. 3. 4National Hospital Organization,Sagamihara National Hospital,Clinical Research Center for Allergy and Rheumatology,Sagamihara,Kanagawa,Japan. 4. 5Department of Respiratory Medicine,Japanese Red Cross Ishinomaki Hospital,Ishinomaki,Miyagi,Japan. 5. 6Tokyo Metropolitan Industrial Technology Research Institute,Koto-ku,Tokyo,Japan. 6. 7Faculty of Agriculture,Iwate University,Morioka,Iwate,Japan. 7. 8Ishinomaki City Hospital, Kaisei Temporary Clinic,Ishinomaki,Miyagi,Japan.
Abstract
BACKGROUND: Indoor mold levels typically increase after natural disasters, flooding, and water damage. Eurotium herbariorum is the sexual stage of Aspergillus glaucus. Case Presentation A 66-year-old, Japanese male, ex-smoker had been diagnosed with bronchial asthma when he was five years old; he achieved remission at the age of 13 years. He was displaced from his home during the Great East Japan Earthquake on March 11, 2011 and moved to temporary housing in Miyagi Prefecture in June 2011. He experienced the first episode of chest tightness, coughing, and wheezing in February 2012, when he again was diagnosed as having bronchial asthma. Mycofloral surveillance detected high counts of Eurotium in the air of his bedroom, kitchen, and living room, with a maximal fungal count of 163,200 colony-forming units per cubic meter (CFU/m3). Although Cladosporium and Penicillium typically predominate in the indoor air of residential dwellings, only low levels of these organisms were present in the patient's home. Morphologic identification confirmed the isolates as E. herbariorum. The patient had positive reactions to E. herbariorum in skin prick testing and the presence of antigen-specific precipitating antibodies to E. herbariorum. Computed tomography of the chest in August 2013 revealed central bronchiectasis and bronchial wall thickening. The patient experienced late reactions after provocation testing with E. herbariorum. CONCLUSION: This report presents the rare case of a patient who developed allergic bronchopulmonary mycosis (ABPM) due to exposure to E. herbariorum during temporary housing after the Great East Japan Earthquake. Oshikata C , Watanabe M , Saito A , Ishida M , Kobayashi S , Konuma R , Kamata Y , Terajima J , Cho J , Yanai M , Tsurikisawa N . Allergic bronchopulmonary mycosis due to exposure to eurotium herbariorum after the Great East Japan Earthquake. Prehosp Disaster Med. 2017;32(6):688-690.
BACKGROUND: Indoor mold levels typically increase after natural disasters, flooding, and water damage. Eurotium herbariorum is the sexual stage of Aspergillus glaucus. Case Presentation A 66-year-old, Japanese male, ex-smoker had been diagnosed with bronchial asthma when he was five years old; he achieved remission at the age of 13 years. He was displaced from his home during the Great East Japan Earthquake on March 11, 2011 and moved to temporary housing in Miyagi Prefecture in June 2011. He experienced the first episode of chest tightness, coughing, and wheezing in February 2012, when he again was diagnosed as having bronchial asthma. Mycofloral surveillance detected high counts of Eurotium in the air of his bedroom, kitchen, and living room, with a maximal fungal count of 163,200 colony-forming units per cubic meter (CFU/m3). Although Cladosporium and Penicillium typically predominate in the indoor air of residential dwellings, only low levels of these organisms were present in the patient's home. Morphologic identification confirmed the isolates as E. herbariorum. The patient had positive reactions to E. herbariorum in skin prick testing and the presence of antigen-specific precipitating antibodies to E. herbariorum. Computed tomography of the chest in August 2013 revealed central bronchiectasis and bronchial wall thickening. The patient experienced late reactions after provocation testing with E. herbariorum. CONCLUSION: This report presents the rare case of a patient who developed allergic bronchopulmonary mycosis (ABPM) due to exposure to E. herbariorum during temporary housing after the Great East Japan Earthquake. Oshikata C , Watanabe M , Saito A , Ishida M , Kobayashi S , Konuma R , Kamata Y , Terajima J , Cho J , Yanai M , Tsurikisawa N . Allergic bronchopulmonary mycosis due to exposure to eurotium herbariorum after the Great East Japan Earthquake. Prehosp Disaster Med. 2017;32(6):688-690.
Entities:
Keywords:
zzm321990 aspergillus fumigatuszzm321990 ; zzm321990 aspergillus glaucuszzm321990 ; zzm321990 eurotium herbariorumzzm321990 ; ABPM allergic bronchopulmonary mycosis; CFU colony-forming units per cubic meter; DG18 dichloran – glycerol agar; DRBC dichloran – rose bengal – chloramphenicol agar; FEV1 forced expiratory volume in one second; Great East Japan Earthquake; allergic bronchopulmonary mycosis