Literature DB >> 28805248

Epigenetics and DNA methylomic profiling in Alzheimer's disease and other neurodegenerative diseases.

Janou A Y Roubroeks1, Rebecca G Smith1, Daniel L A van den Hove2,3, Katie Lunnon1.   

Abstract

Recent studies have suggested a role for epigenetic mechanisms in the complex etiology of various neurodegenerative diseases. In this review, we discuss advances that have been made toward understanding the role of epigenetic processes in neurodegenerative disorders, with a particular focus on Alzheimer's disease, where the most extensive studies have been undertaken to date. We provide a brief overview of DNA modifications, followed by a summarization of studies of DNA modifications in Alzheimer's disease and other neurodegenerative diseases.
© 2017 International Society for Neurochemistry.

Entities:  

Keywords:  Alzheimer's disease; DNA hydroxymethylation; DNA methylation; epigenetic; epigenome-wide association study; genetic

Mesh：

Year:  2017        PMID： 28805248     DOI： 10.1111/jnc.14148

Source DB:  PubMed          Journal:  J Neurochem        ISSN： 0022-3042            Impact factor:   5.372


  25 in total

1.  Formaldehyde, Epigenetics, and Alzheimer's Disease.

Authors:  Fei Wang; Danqi Chen; Peipei Wu; Catherine Klein; Chunyuan Jin
Journal:  Chem Res Toxicol       Date:  2019-04-19       Impact factor: 3.739

2.  Does SCFD1 rs10139154 Polymorphism Decrease Alzheimer's Disease Risk?

Authors:  Polyxeni Stamati; Vasileios Siokas; Athina-Maria Aloizou; Emmanouil Karampinis; Stylianos Arseniou; Valerii N Rakitskii; Aristidis Tsatsakis; Demetrios A Spandidos; Illana Gozes; Panayiotis D Mitsias; Dimitrios P Bogdanos; Georgios M Hadjigeorgiou; Efthimios Dardiotis
Journal:  J Mol Neurosci       Date:  2019-07-02       Impact factor: 3.444

Review 3.  The basis of cellular and regional vulnerability in Alzheimer's disease.

Authors:  Dunja Mrdjen; Edward J Fox; Syed A Bukhari; Kathleen S Montine; Sean C Bendall; Thomas J Montine
Journal:  Acta Neuropathol       Date:  2019-08-07       Impact factor: 17.088

4.  Newborn differential DNA methylation and subcortical brain volumes as early signs of severe neurodevelopmental delay in a South African Birth Cohort Study.

Authors:  Anke Hüls; Catherine J Wedderburn; Nynke A Groenewold; Nicole Gladish; Meaghan J Jones; Nastassja Koen; Julia L MacIsaac; David T S Lin; Katia E Ramadori; Michael P Epstein; Kirsten A Donald; Michael S Kobor; Heather J Zar; Dan J Stein
Journal:  World J Biol Psychiatry       Date:  2022-01-12       Impact factor: 3.418

5.  A gene-level methylome-wide association analysis identifies novel Alzheimer's disease genes.

Authors:  Chong Wu; Jonathan Bradley; Yanming Li; Lang Wu; Hong-Wen Deng
Journal:  Bioinformatics       Date:  2021-02-01       Impact factor: 6.937

Review 6.  The Coming of Age of the Angiotensin Hypothesis in Alzheimer's Disease: Progress Toward Disease Prevention and Treatment?

Authors:  Patrick Gavin Kehoe
Journal:  J Alzheimers Dis       Date:  2018       Impact factor: 4.472

Review 7.  The Role of Activity-Dependent DNA Demethylation in the Adult Brain and in Neurological Disorders.

Authors:  Gonca Bayraktar; Michael R Kreutz
Journal:  Front Mol Neurosci       Date:  2018-05-23       Impact factor: 5.639

8.  Altered Regulation of KIAA0566, and Katanin Signaling Expression in the Locus Coeruleus With Neurofibrillary Tangle Pathology.

Authors:  Pol Andrés-Benito; Raul Delgado-Morales; Isidro Ferrer
Journal:  Front Cell Neurosci       Date:  2018-05-17       Impact factor: 5.505

Review 9.  DNA Methyltransferases, DNA Methylation, and Age-Associated Cognitive Function.

Authors:  Di Cui; Xiangru Xu
Journal:  Int J Mol Sci       Date:  2018-04-28       Impact factor: 5.923

10.  Minimotifs dysfunction is pervasive in neurodegenerative disorders.

Authors:  Surbhi Sharma; Richard J Young; Jingchun Chen; Xiangning Chen; Edwin C Oh; Martin R Schiller
Journal:  Alzheimers Dement (N Y)       Date:  2018-07-25
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