| Literature DB >> 28804822 |
Abstract
Fibrinogen is measured in plasma most commonly using the Clauss method, based on the comparison of thrombin clotting times of dilutions of plasma against a plasma standard. Thrombin time (TT) is a coagulation assay, which reflects the conversion of fibrinogen to fibrin after addition of thrombin reagent. Measurement of clottable fibrinogen and TT allows detecting inborn (congenital) and acquired qualitative and quantitative disorders of fibrinogen that can lead to thrombotic or bleeding events.Entities:
Keywords: Clotting; Fibrin; Fibrinogen; Plasma; Thrombin time
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Year: 2017 PMID： 28804822 DOI： 10.1007/978-1-4939-7196-1_8
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745