R A Slough1, I Caglic2, N L Hansen3, A J Patterson1, T Barrett4. 1. Department of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK. 2. Department of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK. Electronic address: iztokcaglic@gmail.com. 3. Department of Diagnostic and Interventional Radiology, University Hospital Cologne, Cologne, Germany; CamPARI Clinic, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK. 4. Department of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK; CamPARI Clinic, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.
Abstract
AIM: To evaluate the effect of the spasmolytic agent hyoscine butylbromide (HBB) on the quality of anatomical and functional imaging of the prostate. MATERIALS AND METHODS: One hundred and seventy-three patients were included in this retrospective study. Eighty-seven patients received intravenous HBB prior to scanning (HBB group) and 86 patients did not (non-HBB group). Multiparametric (mp) 3 T magnetic resonance imaging (MRI) was performed using a 32-channel body coil. Two radiologists independently evaluated the image quality of T2-weighted imaging (WI), diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) maps, using a five-point Likert scale. DWI was further assessed for distortion and artefact (four-point Likert scale), and T2WI for the presence of motion artefact or blurring. Dynamic contrast-enhanced (DCE) image quality was assessed by recording the number of corrupt contrast curve data points. RESULTS: T2W image quality in the HBB group was significantly higher than in the non-HBB group (3.63±1.11 versus 2.84±0.899); p<0.001. The HBB group also showed significantly less T2W motion and T2W blur than the non-HBB group (23% and 51.7% versus 53.5% and 83.7%, respectively; p<0.001); however, there was no significant improvement in DWI or ADC image quality, or DWI degree of distortion or artefact. There was a trend towards a lower number of corrupted data points from the contrast curve (2.47±2.44 versus 3.68±2.64), but this did not reach significance (p=0.052). CONCLUSION: Administration of HBB significantly improves the image quality of T2WI images. These results provide evidence for the use of HBB in routine patient preparation prior to prostate mpMRI.
AIM: To evaluate the effect of the spasmolytic agent hyoscine butylbromide (HBB) on the quality of anatomical and functional imaging of the prostate. MATERIALS AND METHODS: One hundred and seventy-three patients were included in this retrospective study. Eighty-seven patients received intravenous HBB prior to scanning (HBB group) and 86 patients did not (non-HBB group). Multiparametric (mp) 3 T magnetic resonance imaging (MRI) was performed using a 32-channel body coil. Two radiologists independently evaluated the image quality of T2-weighted imaging (WI), diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) maps, using a five-point Likert scale. DWI was further assessed for distortion and artefact (four-point Likert scale), and T2WI for the presence of motion artefact or blurring. Dynamic contrast-enhanced (DCE) image quality was assessed by recording the number of corrupt contrast curve data points. RESULTS: T2W image quality in the HBB group was significantly higher than in the non-HBB group (3.63±1.11 versus 2.84±0.899); p<0.001. The HBB group also showed significantly less T2W motion and T2W blur than the non-HBB group (23% and 51.7% versus 53.5% and 83.7%, respectively; p<0.001); however, there was no significant improvement in DWI or ADC image quality, or DWI degree of distortion or artefact. There was a trend towards a lower number of corrupted data points from the contrast curve (2.47±2.44 versus 3.68±2.64), but this did not reach significance (p=0.052). CONCLUSION: Administration of HBB significantly improves the image quality of T2WI images. These results provide evidence for the use of HBB in routine patient preparation prior to prostate mpMRI.
Authors: Soudabeh Kargar; Eric A Borisch; Adam T Froemming; Roger C Grimm; Akira Kawashima; Bernard F King; Eric G Stinson; Stephen J Riederer Journal: Magn Reson Med Date: 2020-05-17 Impact factor: 4.668
Authors: Cynthia Schmidt; Andreas M Hötker; Urs J Muehlematter; Irene A Burger; Olivio F Donati; Borna K Barth Journal: Abdom Radiol (NY) Date: 2021-03-26
Authors: Mehmet Coskun; Sherif Mehralivand; Joanna H Shih; Maria J Merino; Bradford J Wood; Peter A Pinto; Tristan Barrett; Peter L Choyke; Baris Turkbey Journal: Abdom Radiol (NY) Date: 2020-12
Authors: Eric A Borisch; Roger C Grimm; Soudabeh Kargar; Akira Kawashima; Phillip J Rossman; Stephen J Riederer Journal: Magn Reson Med Date: 2020-09-24 Impact factor: 4.668
Authors: Francesco Giganti; Veeru Kasivisvanathan; Alex Kirkham; Shonit Punwani; Mark Emberton; Caroline M Moore; Clare Allen Journal: Br J Radiol Date: 2021-07-08 Impact factor: 3.039