| Literature DB >> 28795696 |
Guangyue Li1, Miguel A Maria-Solano2, Adrian Romero-Rivera2, Sílvia Osuna2, Manfred T Reetz1.
Abstract
The long-standing problem of achieving high activity of a thermophilic enzyme at low temperatures and short reaction times with little tradeoff in thermostability has been solved by directed evolution, an alcohol dehydrogenase found in hot springs serving as the catalyst in enantioselective ketone reductions.Entities:
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Year: 2017 PMID： 28795696 DOI： 10.1039/c7cc05377k
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222