Literature DB >> 28784825

p38α: A Profibrotic Signaling Nexus.

Matthew S Stratton1, Keith A Koch1, Timothy A McKinsey2.   

Abstract

Entities:  

Keywords:  Editorials; fibrosis; heart; inhibitor; kinase; myofibroblast

Mesh：

Substances：

Year:  2017        PMID： 28784825      PMCID： PMC5709048          DOI： 10.1161/CIRCULATIONAHA.117.028957

Source DB:  PubMed          Journal:  Circulation        ISSN： 0009-7322            Impact factor:   29.690


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  14 in total

1.  A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo.

Authors:  Jennifer Davis; Adam R Burr; Gregory F Davis; Lutz Birnbaumer; Jeffery D Molkentin
Journal:  Dev Cell       Date:  2012-09-27       Impact factor: 12.270

Review 2.  "Go upstream, young man": lessons learned from the p38 saga.

Authors:  D Hammaker; G S Firestein
Journal:  Ann Rheum Dis       Date:  2010-01       Impact factor: 19.103

3.  A protein kinase involved in the regulation of inflammatory cytokine biosynthesis.

Authors:  J C Lee; J T Laydon; P C McDonnell; T F Gallagher; S Kumar; D Green; D McNulty; M J Blumenthal; J R Heys; S W Landvatter; J E Strickler; M M McLaughlin; I R Siemens; S M Fisher; G P Livi; J R White; J L Adams; P R Young
Journal:  Nature       Date:  1994 Dec 22-29       Impact factor: 49.962

Review 4.  Targeted Therapy for Idiopathic Pulmonary Fibrosis: Where To Now?

Authors:  Sunad Rangarajan; Morgan L Locy; Tracy R Luckhardt; Victor J Thannickal
Journal:  Drugs       Date:  2016-03       Impact factor: 9.546

Review 5.  The effect of renin-angiotensin system inhibitors on mortality and heart failure hospitalization in patients with heart failure and preserved ejection fraction: a systematic review and meta-analysis.

Authors:  Ravi V Shah; Akshay S Desai; Michael M Givertz
Journal:  J Card Fail       Date:  2010-01-06       Impact factor: 5.712

6.  Fibroblast-Specific Genetic Manipulation of p38 Mitogen-Activated Protein Kinase In Vivo Reveals Its Central Regulatory Role in Fibrosis.

Authors:  Jeffery D Molkentin; Darrian Bugg; Natasha Ghearing; Lisa E Dorn; Peter Kim; Michelle A Sargent; Jagadambika Gunaje; Kinya Otsu; Jennifer Davis
Journal:  Circulation       Date:  2017-03-29       Impact factor: 29.690

Review 7.  Murine models of pulmonary fibrosis.

Authors:  Bethany B Moore; Cory M Hogaboam
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2007-11-09       Impact factor: 5.464

8.  Effect of Losmapimod on Cardiovascular Outcomes in Patients Hospitalized With Acute Myocardial Infarction: A Randomized Clinical Trial.

Authors:  Michelle L O'Donoghue; Ruchira Glaser; Matthew A Cavender; Philip E Aylward; Marc P Bonaca; Andrzej Budaj; Richard Y Davies; Mikael Dellborg; Keith A A Fox; Jorge Antonio T Gutierrez; Christian Hamm; Robert G Kiss; František Kovar; Julia F Kuder; Kyung Ah Im; John J Lepore; Jose L Lopez-Sendon; Ton Oude Ophuis; Alexandr Parkhomenko; Jennifer B Shannon; Jindrich Spinar; Jean-Francois Tanguay; Mikhail Ruda; P Gabriel Steg; Pierre Theroux; Stephen D Wiviott; Ian Laws; Marc S Sabatine; David A Morrow
Journal:  JAMA       Date:  2016-04-19       Impact factor: 56.272

9.  An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis.

Authors:  R Gisli Jenkins; Bethany B Moore; Rachel C Chambers; Oliver Eickelberg; Melanie Königshoff; Martin Kolb; Geoffrey J Laurent; Carmel B Nanthakumar; Mitchell A Olman; Annie Pardo; Moises Selman; Dean Sheppard; Patricia J Sime; Andrew M Tager; Amanda L Tatler; Victor J Thannickal; Eric S White
Journal:  Am J Respir Cell Mol Biol       Date:  2017-05       Impact factor: 7.748

Review 10.  The case for inhibiting p38 mitogen-activated protein kinase in heart failure.

Authors:  Pelin Arabacilar; Michael Marber
Journal:  Front Pharmacol       Date:  2015-05-12       Impact factor: 5.810
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  4 in total

1.  Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation.

Authors:  Matthew S Stratton; Rushita A Bagchi; Marina B Felisbino; Rachel A Hirsch; Harrison E Smith; Andrew S Riching; Blake Y Enyart; Keith A Koch; Maria A Cavasin; Michael Alexanian; Kunhua Song; Jun Qi; Madeleine E Lemieux; Deepak Srivastava; Maggie P Y Lam; Saptarsi M Haldar; Charles Y Lin; Timothy A McKinsey
Journal:  Circ Res       Date:  2019-08-14       Impact factor: 17.367

2.  Cardiac fibrosis in oncologic therapies.

Authors:  René R Sevag Packard
Journal:  Curr Opin Physiol       Date:  2022-08-08

Review 3.  Therapeutic targets for cardiac fibrosis: from old school to next-gen.

Authors:  Joshua G Travers; Charles A Tharp; Marcello Rubino; Timothy A McKinsey
Journal:  J Clin Invest       Date:  2022-03-01       Impact factor: 14.808

4.  Cardiac fibroblast-specific p38α MAP kinase promotes cardiac hypertrophy via a putative paracrine interleukin-6 signaling mechanism.

Authors:  Sumia A Bageghni; Karen E Hemmings; Ngonidzashe Zava; Christopher P Denton; Karen E Porter; Justin F X Ainscough; Mark J Drinkhill; Neil A Turner
Journal:  FASEB J       Date:  2018-03-30       Impact factor: 5.191
  4 in total

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