Literature DB >> 28781716

Short Communication: Studying the Role of Smart Flare Gold Nano Particles in Studying Micro RNA and Oncogene Differential Expression in Prostate Cancer Cell Lines.

Hirendra Banerjee1, Jamel Joyner1, Monet Stevenson1, William Kaha1, Christopher Krauss1, Sasha Hodges1, Eduardo Santos1, Myla Worthington1, Jeffferey Rousch1, Gloria Payne1, Vinod Manglik1, Narendra Banerjee1, Brianna Morris1, Dayton Bell1, Santosh Mandal2.   

Abstract

Nano technology is a cutting edge science which is now effectively used in the field of cancer biology. Smart Flare gold nanoparticles are now used often for differential gene expression analysis. In this manuscript we are reporting the use of micro RNA miR 146a and onco gene EZH2 Smart Flare probes to study their expression in different prostate cancer cell lines and the effect of novel Rhenium compounds on these genes using a flow cytometer and a Fluorescence microscope. Our results showed this novel nanotechnology can be effectively used in cancer biology to successfully detect the effect of novel drugs on oncogenes and could be a very useful tool for next generation of cancer researchers.

Entities:  

Keywords:  Nanoparticles; gene expression; micro RNA

Year:  2017        PMID： 28781716      PMCID： PMC5542019          DOI： 10.6000/1929-2279.2017.06.02.1

Source DB:  PubMed          Journal:  J Can Res Updates


  15 in total

1.  Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression.

Authors:  Li-Hui Wang; Seok-Hyung Kim; Jung Hyun Lee; Yoon-La Choi; Young Chul Kim; Tae Sung Park; Yun-Chul Hong; Chun-Fu Wu; Young Kee Shin
Journal:  Clin Cancer Res       Date:  2007-01-01       Impact factor: 12.531

2.  The role of microRNA genes in papillary thyroid carcinoma.

Authors:  Huiling He; Krystian Jazdzewski; Wei Li; Sandya Liyanarachchi; Rebecca Nagy; Stefano Volinia; George A Calin; Chang-Gong Liu; Kaarle Franssila; Saul Suster; Richard T Kloos; Carlo M Croce; Albert de la Chapelle
Journal:  Proc Natl Acad Sci U S A       Date:  2005-12-19       Impact factor: 11.205

3.  Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells.

Authors:  D Bhaumik; G K Scott; S Schokrpur; C K Patil; J Campisi; C C Benz
Journal:  Oncogene       Date:  2008-05-26       Impact factor: 9.867

4.  Signatures of microRNAs and selected microRNA target genes in human melanoma.

Authors:  Demetra Philippidou; Martina Schmitt; Dirk Moser; Christiane Margue; Petr V Nazarov; Arnaud Muller; Laurent Vallar; Dorothee Nashan; Iris Behrmann; Stephanie Kreis
Journal:  Cancer Res       Date:  2010-05-04       Impact factor: 12.701

5.  Targeting Smad4 links microRNA-146a to the TGF-beta pathway during retinoid acid induction in acute promyelocytic leukemia cell line.

Authors:  Hua Zhong; Hai-rong Wang; Shuang Yang; Ji-hua Zhong; Ting Wang; Chun Wang; Fang-yuan Chen
Journal:  Int J Hematol       Date:  2010-06-25       Impact factor: 2.490

6.  mRNA detection in living cells: A next generation cancer stem cell identification technique.

Authors:  Steven McClellan; Jaroslav Slamecka; Patrick Howze; Lee Thompson; Michael Finan; Rodney Rocconi; Laurie Owen
Journal:  Methods       Date:  2015-04-25       Impact factor: 3.608

7.  Up-regulated microRNA-146a negatively modulate Helicobacter pylori-induced inflammatory response in human gastric epithelial cells.

Authors:  Zhen Liu; Bin Xiao; Bin Tang; Bosheng Li; Na Li; Endong Zhu; Gang Guo; Jiang Gu; Yuan Zhuang; Xiaofei Liu; Honglei Ding; Xiaoyan Zhao; Hong Guo; Xuhu Mao; Quanming Zou
Journal:  Microbes Infect       Date:  2010-06-11       Impact factor: 2.700

8.  Differential microRNA expression profiling of mesothelioma and expression analysis of miR-1 and miR-214 in mesothelioma.

Authors:  Vishwa Jeet Amatya; Amany Sayed Mawas; Kei Kushitani; Mouchira M Mohi El-Din; Yukio Takeshima
Journal:  Int J Oncol       Date:  2016-01-26       Impact factor: 5.650

9.  Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth.

Authors:  Xiaohong Wang; Shuang Tang; Shu-Yun Le; Robert Lu; Janet S Rader; Craig Meyers; Zhi-Ming Zheng
Journal:  PLoS One       Date:  2008-07-02       Impact factor: 3.240

10.  A microRNA expression signature of human solid tumors defines cancer gene targets.

Authors:  Stefano Volinia; George A Calin; Chang-Gong Liu; Stefan Ambs; Amelia Cimmino; Fabio Petrocca; Rosa Visone; Marilena Iorio; Claudia Roldo; Manuela Ferracin; Robyn L Prueitt; Nozumu Yanaihara; Giovanni Lanza; Aldo Scarpa; Andrea Vecchione; Massimo Negrini; Curtis C Harris; Carlo M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  2006-02-03       Impact factor: 11.205
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  2 in total

Review 1.  RNA Flow Cytometry for the Study of T Cell Metabolism.

Authors:  Alessandra Rossi; Ilenia Pacella; Silvia Piconese
Journal:  Int J Mol Sci       Date:  2021-04-09       Impact factor: 5.923

2.  SmartFlareTM is a reliable method for assessing mRNA expression in single neural stem cells.

Authors:  Andrea Diana; Maria Dolores Setzu; Zaal Kokaia; Roxana Nat; Cristina Maxia; Daniela Murtas
Journal:  World J Stem Cells       Date:  2021-12-26       Impact factor: 5.326
  2 in total

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