| Literature DB >> 28781093 |
Marlene Penz1, Tobias Stalder2, Robert Miller3, Vera M Ludwig4, Magdalena K Kanthak4, Clemens Kirschbaum4.
Abstract
Burnout is a syndrome with negative impact on cognitive performance and mood as a consequence of long-term stress at work. It is further associated with increased risk for mental and physical diseases. One potential pathway to mediate chronic work-stress and adverse health conditions in burnout is through alterations in long-term glucocorticoid secretion. Here, we present cross-sectional data on hair cortisol/cortisone (hairF/hairE) concentrations and burnout from a population-based sample of the Dresden Burnout Study (DBS; N=314 hair samples). Burnout symptoms (emotional exhaustion, cynical attitudes toward work, and reduced efficacy) were assessed with the Maslach Burnout Inventory-General Survey (MBI-GS). To control for potential confounds, depressivity was as well assessed using the Patient Health Questionnaire (PHQ-9) screening instrument for major depression. The present findings indicate specific hypercortisolism in participants who suffer from burnout. No significant associations were found between depressivity and hairF/hairE.Entities:
Keywords: Biomarkers; Burnout; Depression; Glucocorticoids; Hair cortisol
Mesh:
Substances:
Year: 2017 PMID: 28781093 DOI: 10.1016/j.psyneuen.2017.07.485
Source DB: PubMed Journal: Psychoneuroendocrinology ISSN: 0306-4530 Impact factor: 4.905