Literature DB >> 29611872

The Dresden Burnout Study: Protocol of a prospective cohort study for the bio-psychological investigation of burnout.

Marlene Penz1, Magdalena K Wekenborg1, Lars Pieper2, Katja Beesdo-Baum2, Andreas Walther1, Robert Miller1, Tobias Stalder1,3, Clemens Kirschbaum1.   

Abstract

OBJECTIVES: The Dresden Burnout Study (DBS) is a 12-year longitudinal cohort study that aims to provide a description of the burnout syndrome on the basis of time and symptom criteria with a special focus on the search for biomarkers. Biological and psychosocial approaches are applied to examine the long-term course and consequences of burnout within a population-based German-speaking sample aged 18 to 68 years.
METHODS: Demographics and psychosocial data are generated by online assessments, including demographics and questionnaires on burnout, burnout-related constructs, work-environment, and health-related factors. The lab-based biomarker assessment includes endocrine, physiological, immunological, and epigenetic markers obtained from blood and hair samples. In addition, heart rate variability is also measured repeatedly. Within the first 2 years, the DBS collected psychosocial data from over 7,600 participants with biological data obtained from more than 800 individuals. During the following 10 years, detailed assessments of biomarkers and psychosocial factors will be collected in annual study waves.
RESULTS: Results will be generated during the following decade.
CONCLUSION: The findings of the DBS are expected to pave the road for an in-depth biopsychosocial characterization of burnout and to give insight into the long-term course and potential mental and physical health consequences of the burnout syndrome.
Copyright © 2018 John Wiley & Sons, Ltd.

Entities:  

Keywords:  biomarker; biopsychosocial assessment; burnout; chronic work stress; prospective cohort study

Mesh:

Substances:

Year:  2018        PMID: 29611872      PMCID: PMC6877172          DOI: 10.1002/mpr.1613

Source DB:  PubMed          Journal:  Int J Methods Psychiatr Res        ISSN: 1049-8931            Impact factor:   4.035


  72 in total

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2.  Insufficient sleep predicts clinical burnout.

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Review 3.  LC-MS based analysis of endogenous steroid hormones in human hair.

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4.  The relationship between job-related burnout and depressive disorders--results from the Finnish Health 2000 Study.

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5.  Quantitative analysis of steroid hormones in human hair using a column-switching LC-APCI-MS/MS assay.

Authors:  Wei Gao; Tobias Stalder; Paul Foley; Manfred Rauh; Huihua Deng; Clemens Kirschbaum
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6.  Association between burnout and circulating levels of pro- and anti-inflammatory cytokines in schoolteachers.

Authors:  Roland von Känel; Silja Bellingrath; Brigitte M Kudielka
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7.  Fatigue, burnout, and chronic fatigue syndrome among employees on sick leave: do attributions make the difference?

Authors:  M J H Huibers; A J H M Beurskens; J B Prins; I J Kant; E Bazelmans; C P Van Schayck; J A Knottnerus; G Bleijenberg
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Review 8.  Human models in acute and chronic stress: assessing determinants of individual hypothalamus-pituitary-adrenal axis activity and reactivity.

Authors:  Brigitte M Kudielka; Stefan Wüst
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9.  Common Genetic Variation Near Melatonin Receptor 1A Gene Linked to Job-Related Exhaustion in Shift Workers.

Authors:  Sonja Sulkava; Hanna M Ollila; Jukka Alasaari; Sampsa Puttonen; Mikko Härmä; Katriina Viitasalo; Alexandra Lahtinen; Jaana Lindström; Auli Toivola; Raimo Sulkava; Mika Kivimäki; Jussi Vahtera; Timo Partonen; Kaisa Silander; Tarja Porkka-Heiskanen; Tiina Paunio
Journal:  Sleep       Date:  2017-01-01       Impact factor: 5.849

10.  Burnout Is Associated with Reduced Parasympathetic Activity and Reduced HPA Axis Responsiveness, Predominantly in Males.

Authors:  Wieke de Vente; Jan G C van Amsterdam; Miranda Olff; Jan H Kamphuis; Paul M G Emmelkamp
Journal:  Biomed Res Int       Date:  2015-10-18       Impact factor: 3.411

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  8 in total

1.  The Longitudinal Association of Reduced Vagal Tone With Burnout.

Authors:  Magdalena K Wekenborg; LaBarron K Hill; Julian F Thayer; Marlene Penz; Ralf Arne Wittling; Clemens Kirschbaum
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2.  Examining reactivity patterns in burnout and other indicators of chronic stress.

Authors:  Magdalena K Wekenborg; Bernadette von Dawans; LaBarron K Hill; Julian F Thayer; Marlene Penz; Clemens Kirschbaum
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3.  Associations between burnout symptoms and social behaviour: exploring the role of acute stress and vagal function.

Authors:  Magdalena K Wekenborg; LaBarron K Hill; Pia Grabbe; Julian F Thayer; Clemens Kirschbaum; Susan Lindenlaub; Ralf Arne Wittling; Bernadette von Dawans
Journal:  BMC Public Health       Date:  2022-05-05       Impact factor: 4.135

4.  Epigenetic perspective on the role of brain-derived neurotrophic factor in burnout.

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Journal:  Transl Psychiatry       Date:  2020-10-19       Impact factor: 6.222

5.  Demographic Factors and Job Characteristics Associated With Burnout in Chinese Female Nurses During Controlled COVID-19 Period: A Cross-Sectional Study.

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6.  Determining the direction of prediction of the association between parasympathetic dysregulation and exhaustion symptoms.

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7.  High-frequency variability in heart rate is related to COVID-19-associated worries six years later.

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8.  The moderating effect of cortisol and dehydroepiandrosterone on the relation between sleep and depression or burnout.

Authors:  Nicole Rothe; Sabrina Vogel; Kristin Schmelzer; Clemens Kirschbaum; Marlene Penz; Magdalena Katharina Wekenborg; Wei Gao; Andreas Walther
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  8 in total

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