Literature DB >> 28777447

Technical Note: Using experimentally determined proton spot scanning timing parameters to accurately model beam delivery time.

Jiajian Shen1, Erik Tryggestad2, James E Younkin1, Sameer R Keole1, Keith M Furutani2, Yixiu Kang1, Michael G Herman2, Martin Bues1.   

Abstract

PURPOSE: To accurately model the beam delivery time (BDT) for a synchrotron-based proton spot scanning system using experimentally determined beam parameters.
METHODS: A model to simulate the proton spot delivery sequences was constructed, and BDT was calculated by summing times for layer switch, spot switch, and spot delivery. Test plans were designed to isolate and quantify the relevant beam parameters in the operation cycle of the proton beam therapy delivery system. These parameters included the layer switch time, magnet preparation and verification time, average beam scanning speeds in x- and y-directions, proton spill rate, and maximum charge and maximum extraction time for each spill. The experimentally determined parameters, as well as the nominal values initially provided by the vendor, served as inputs to the model to predict BDTs for 602 clinical proton beam deliveries. The calculated BDTs (TBDT ) were compared with the BDTs recorded in the treatment delivery log files (TLog ): ∆t = TLog -TBDT .
RESULTS: The experimentally determined average layer switch time for all 97 energies was 1.91 s (ranging from 1.9 to 2.0 s for beam energies from 71.3 to 228.8 MeV), average magnet preparation and verification time was 1.93 ms, the average scanning speeds were 5.9 m/s in x-direction and 19.3 m/s in y-direction, the proton spill rate was 8.7 MU/s, and the maximum proton charge available for one acceleration is 2.0 ± 0.4 nC. Some of the measured parameters differed from the nominal values provided by the vendor. The calculated BDTs using experimentally determined parameters matched the recorded BDTs of 602 beam deliveries (∆t = -0.49 ± 1.44 s), which were significantly more accurate than BDTs calculated using nominal timing parameters (∆t = -7.48 ± 6.97 s).
CONCLUSIONS: An accurate model for BDT prediction was achieved by using the experimentally determined proton beam therapy delivery parameters, which may be useful in modeling the interplay effect and patient throughput. The model may provide guidance on how to effectively reduce BDT and may be used to identifying deteriorating machine performance.
© 2017 American Association of Physicists in Medicine.

Entities:  

Keywords:  beam delivery time; layer switch time; proton beam therapy; proton spot scanning; spot spill time; spot switch time

Mesh:

Year:  2017        PMID: 28777447     DOI: 10.1002/mp.12504

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  15 in total

1.  Impact of Spot Size and Spacing on the Quality of Robustly Optimized Intensity Modulated Proton Therapy Plans for Lung Cancer.

Authors:  Chenbin Liu; Steven E Schild; Joe Y Chang; Zhongxing Liao; Shawn Korte; Jiajian Shen; Xiaoning Ding; Yanle Hu; Yixiu Kang; Sameer R Keole; Terence T Sio; William W Wong; Narayan Sahoo; Martin Bues; Wei Liu
Journal:  Int J Radiat Oncol Biol Phys       Date:  2018-02-14       Impact factor: 7.038

2.  Intensity-modulated proton therapy (IMPT) interplay effect evaluation of asymmetric breathing with simultaneous uncertainty considerations in patients with non-small cell lung cancer.

Authors:  Jie Shan; Yunze Yang; Steven E Schild; Thomas B Daniels; William W Wong; Mirek Fatyga; Martin Bues; Terence T Sio; Wei Liu
Journal:  Med Phys       Date:  2020-10-13       Impact factor: 4.071

3.  Synchrotron-Based Pencil Beam Scanning Nozzle with an Integrated Mini-Ridge Filter: A Dosimetric Study to Optimize Treatment Delivery.

Authors:  Xianliang Wang; Yupeng Li; Xiaodong Zhang; Heng Li; Koichi Miyazaki; Rintaro Fujimoto; Hiroshi Akiyama; Michael T Gillin; Falk Poenisch; Narayan Sahoo; David Grosshans; Brandon Gunn; Steven Jay Frank; Pei Wang; Jinyi Lang; Qing Hou; Xiaorong Ronald Zhu
Journal:  Cancers (Basel)       Date:  2017-12-13       Impact factor: 6.639

4.  Small-spot intensity-modulated proton therapy and volumetric-modulated arc therapies for patients with locally advanced non-small-cell lung cancer: A dosimetric comparative study.

Authors:  Chenbin Liu; Terence T Sio; Wei Deng; Jie Shan; Thomas B Daniels; William G Rule; Pedro R Lara; Shawn M Korte; Jiajian Shen; Xiaoning Ding; Steven E Schild; Martin Bues; Wei Liu
Journal:  J Appl Clin Med Phys       Date:  2018-10-17       Impact factor: 2.102

5.  Multiple energy extraction reduces beam delivery time for a synchrotron-based proton spot-scanning system.

Authors:  James E Younkin; Martin Bues; Terence T Sio; Wei Liu; Xiaoning Ding; Sameer R Keole; Joshua B Stoker; Jiajian Shen
Journal:  Adv Radiat Oncol       Date:  2018-02-23

6.  Optimization of motion management parameters in a synchrotron-based spot scanning system.

Authors:  Jedediah E Johnson; Michael G Herman; Jon J Kruse
Journal:  J Appl Clin Med Phys       Date:  2019-09       Impact factor: 2.102

7.  Functional avoidance-based intensity modulated proton therapy with 4DCT derived ventilation imaging for lung cancer.

Authors:  Jingjing M Dougherty; Edward Castillo; Richard Castillo; Austin M Faught; Mark Pepin; Sean S Park; Chris J Beltran; Thomas Guerrero; Inga Grills; Yevgeniy Vinogradskiy
Journal:  J Appl Clin Med Phys       Date:  2021-06-22       Impact factor: 2.102

8.  Technical Note: Multiple energy extraction techniques for synchrotron-based proton delivery systems may exacerbate motion interplay effects in lung cancer treatments.

Authors:  James E Younkin; Danairis Hernandez Morales; Jiajian Shen; Xiaoning Ding; Joshua B Stoker; Nathan Y Yu; Terence T Sio; Thomas B Daniels; Martin Bues; Mirek Fatyga; Steven E Schild; Wei Liu
Journal:  Med Phys       Date:  2021-07-29       Impact factor: 4.506

9.  Clinical Validation of a Ray-Casting Analytical Dose Engine for Spot Scanning Proton Delivery Systems.

Authors:  James E Younkin; Danairis Hernandez Morales; Jiajian Shen; Jie Shan; Martin Bues; Jarrod M Lentz; Steven E Schild; Joshua B Stoker; Xiaoning Ding; Wei Liu
Journal:  Technol Cancer Res Treat       Date:  2019 Jan-Dec

10.  Quantitative analysis of treatments using real-time image gated spot-scanning with synchrotron-based proton beam therapy system log data.

Authors:  Takaaki Yoshimura; Shinichi Shimizu; Takayuki Hashimoto; Kentaro Nishioka; Norio Katoh; Hiroshi Taguchi; Koichi Yasuda; Taeko Matsuura; Seishin Takao; Masaya Tamura; Sodai Tanaka; Yoichi M Ito; Yuto Matsuo; Hiroshi Tamura; Kenji Horita; Kikuo Umegaki; Hiroki Shirato
Journal:  J Appl Clin Med Phys       Date:  2020-11-05       Impact factor: 2.102

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