| Literature DB >> 28777120 |
Rine Nakanishi1, Wendy S Post2,3, Kazuhiro Osawa1, Eranthi Jayawardena1, Michael Kim1, Nasim Sheidaee1, Negin Nezarat1, Sina Rahmani1, Nicholas Kim1, Nicolai Hathiramani1, Shriraj Susarla1, Frank Palella4, Mallory Witt5, Michael J Blaha2,6, Todd T Brown6, Lawrence Kingsley7,8, Sabina A Haberlen3, Christopher Dailing1, Matthew J Budoff1.
Abstract
BACKGROUND AND AIM: The association of HIV with coronary atherosclerosis has been established; however, the progression of coronary atherosclerosis over time among participants with HIV is not well known. The Multicenter AIDS Cohort Study Quantitative Coronary Plaque Progression Study is a large prospective multicenter study quantifying progression of coronary plaque assessed by serial coronary computed tomography angiography (CTA). PATIENTS AND METHODS: HIV-infected and uninfected men who were enrolled in the Multicenter AIDS Cohort Study Cardiovascular Substudy were eligible to complete a follow-up contrast coronary CTA 3-6 years after baseline. We measured coronary plaque volume and characteristics (calcified and noncalcified plaque including fibrous, fibrous-fatty, and low attenuation) and vulnerable plaque among HIV-infected and uninfected men using semiautomated plaque software to investigate the progression of coronary atherosclerosis over time.Entities:
Mesh:
Year: 2018 PMID: 28777120 PMCID: PMC5722668 DOI: 10.1097/MCA.0000000000000546
Source DB: PubMed Journal: Coron Artery Dis ISSN: 0954-6928 Impact factor: 1.439