Literature DB >> 28772172

Naloxone use among overdose prevention trainees in New York City: A longitudinal cohort study.

Anne Siegler1, Zina Huxley-Reicher2, Lara Maldjian3, Robyn Jordan4, Chloe Oliver5, Andrea Jakubowski6, Hillary V Kunins7.   

Abstract

BACKGROUND: Providing naloxone to laypersons who are likely to witness an opioid overdose is now a widespread public health response to the national opioid overdose epidemic. Estimating the proportion of individuals who use naloxone can define its potential impact to reduce overdose deaths at a population level. We determined the proportion of study participants who used naloxone within 12 months following training and factors associated with witnessing overdose and naloxone use.
METHODS: We conducted a prospective, observational study of individuals completing overdose prevention training (OPT) between June and September 2013. Participants were recruited from New York City's six largest overdose prevention programs, all operated by syringe exchange programs. Questionnaires were administered at four time points over 12 months. Main outcomes were witnessing or experiencing overdose, and naloxone administration.
RESULTS: Of 675 individuals completing OPT, 429 (64%) were approached and 351 (52%) were enrolled. Overall, 299 (85%) study participants completed at least one follow-up survey; 128 (36%) witnessed at least one overdose. Of 312 witnessed opioid overdoses, naloxone was administered in 241 events (77%); 188 (60%) by the OPT study participant. Eighty-six (25%) study participants administered naloxone at least once. Over one third of study participants (30, 35%) used naloxone 6 or more months after training.
CONCLUSIONS: Witnessing an overdose and naloxone use was common among this study cohort of OPT trainees. Training individuals at high risk for witnessing overdoses may reduce opioid overdose mortality at a population level if sufficient numbers of potential responders are equipped with naloxone.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Morbidity; Naloxone; Opiate; Opioid; Overdose; Prevention

Mesh:

Substances:

Year:  2017        PMID: 28772172     DOI: 10.1016/j.drugalcdep.2017.06.029

Source DB:  PubMed          Journal:  Drug Alcohol Depend        ISSN: 0376-8716            Impact factor:   4.492


  8 in total

1.  Development and evaluation of a pilot overdose education and naloxone distribution program for hospitalized general medical patients.

Authors:  Andrea Jakubowski; Alexander Pappas; Lee Isaacsohn; Felipe Castillo; Mariya Masyukova; Richard Silvera; Louisa Holaday; Evan Rausch; Sameen Farooq; Keith T Veltri; Chinazo O Cunningham; Marcus A Bachhuber
Journal:  Subst Abus       Date:  2018-11-26       Impact factor: 3.716

2.  Who is using take-home naloxone? An examination of supersavers.

Authors:  Desiree Eide; Philipp Lobmaier; Thomas Clausen
Journal:  Harm Reduct J       Date:  2022-06-18

3.  Community-Based Response to Fentanyl Overdose Outbreak, San Francisco, 2015.

Authors:  Christopher Rowe; Eliza Wheeler; T Stephen Jones; Clement Yeh; Phillip O Coffin
Journal:  J Urban Health       Date:  2019-02       Impact factor: 3.671

4.  Patient characteristics associated with being offered take home naloxone in a busy, urban emergency department: a retrospective chart review.

Authors:  Daniel C O'Brien; Daniel Dabbs; Kathryn Dong; Paul J Veugelers; Elaine Hyshka
Journal:  BMC Health Serv Res       Date:  2019-09-05       Impact factor: 2.655

Review 5.  New and Emerging Opioid Overdose Risk Factors.

Authors:  Ralph Foglia; Anna Kline; Nina A Cooperman
Journal:  Curr Addict Rep       Date:  2021-04-22

6.  How do naloxone-based interventions work to reduce overdose deaths: a realist review.

Authors:  Nicole M Miller; Bethany Waterhouse-Bradley; Claire Campbell; Gillian W Shorter
Journal:  Harm Reduct J       Date:  2022-02-23

7.  Retrospective analysis of patterns of opioid overdose and interventions delivered at a tertiary hospital emergency department: impact of COVID-19.

Authors:  Katherine L Potaka; Rebecca Freeman; Danny Soo; Nam-Anh Nguyen; Tin Fei Sim; Joanna C Moullin
Journal:  BMC Emerg Med       Date:  2022-04-09

8.  Community Case Study of Naloxone Distribution by Hospital-Based Harm Reduction Program for People Who Use Drugs in New York City.

Authors:  Farah Riazi; Wilma Toribio; Emaun Irani; Terence M Hughes; Zina Huxley-Reicher; Elisa McBratney; Trang Vu; Keith Sigel; Jeffrey J Weiss
Journal:  Front Sociol       Date:  2021-07-07
  8 in total

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