Literature DB >> 30475162

Development and evaluation of a pilot overdose education and naloxone distribution program for hospitalized general medical patients.

Andrea Jakubowski1,2, Alexander Pappas2, Lee Isaacsohn2, Felipe Castillo3, Mariya Masyukova2, Richard Silvera1,2, Louisa Holaday1,2, Evan Rausch1,2, Sameen Farooq1,2, Keith T Veltri4,5, Chinazo O Cunningham1, Marcus A Bachhuber1.   

Abstract

Background: Overdose education and naloxone distribution (OEND) to people at risk of witnessing or experiencing an opioid overdose has traditionally been provided through harm reduction agencies. Expanding OEND to inpatient general medical settings may reach at-risk individuals who do not access harm reduction services and have not been trained. An OEND program targeting inpatients was developed, piloted, and evaluated on 2 general medicine floors at Montefiore Medical Center, a large urban academic medical center in Bronx, New York.
Methods: The planning committee consisted of 10 resident physicians and 2 faculty mentors. A consult service model was piloted, whereby the primary inpatient care team paged the consult team (consisting of rotating members from the planning committee) for any newly admitted patient who had used any opioid in the year prior to admission. Consult team members assessed patients for eligibility and provided OEND to eligible patients through a short video training. Upon completion, patients received a take-home naloxone kit. To evaluate the program, a retrospective chart review over the first year (April 2016 to March 2017) of the pilot was conducted.
Results: Overall, consults on 80 patients were received. Of these, 74 were eligible and the consult team successfully trained 50 (68%). Current opioid analgesic use of ≥50 morphine milligram equivalents daily was the most common eligibility criterion met (38%). Twenty-four percent of patients were admitted for an opioid-related adverse event, the most common being opioid overdose (9%), then opioid withdrawal (8%), skin complication related to injecting (5%), and opioid intoxication (2%). Twenty-five percent had experienced an overdose, 35% had witnessed an overdose in their lifetime, and 83% had never received OEND previously. Conclusions: Integrating OEND into general inpatient medical care is possible and can reach high-risk patients who have not received OEND previously. Future research should identify the optimal way of implementing this service.

Entities:  

Keywords:  drug overdose; hospitalization; naloxone; opioid analgesics

Mesh:

Substances:

Year:  2018        PMID: 30475162      PMCID: PMC6778336          DOI: 10.1080/08897077.2018.1518836

Source DB:  PubMed          Journal:  Subst Abus        ISSN: 0889-7077            Impact factor:   3.716


  17 in total

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Journal:  Ann Emerg Med       Date:  2016-10-10       Impact factor: 5.721

2.  Indian Health Service pharmacists engaged in opioid safety initiatives and expanding access to naloxone.

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Journal:  J Am Pharm Assoc (2003)       Date:  2017 Mar - Apr

3.  Opioid overdose education and naloxone distribution: Development of the Veterans Health Administration's national program.

Authors:  Elizabeth M Oliva; Melissa L D Christopher; Daina Wells; Mark Bounthavong; Michael Harvey; Julianne Himstreet; Thomas Emmendorfer; Michael Valentino; Mariano Franchi; Francine Goodman; Jodie A Trafton
Journal:  J Am Pharm Assoc (2003)       Date:  2017 Mar - Apr

4.  Implementing an overdose education and naloxone distribution program in a health system.

Authors:  Jennifer Devries; Sally Rafie; Gregory Polston
Journal:  J Am Pharm Assoc (2003)       Date:  2017-02-21

5.  Naloxone for opioid overdose prevention: pharmacists' role in community-based practice settings.

Authors:  Abby M Bailey; Daniel P Wermeling
Journal:  Ann Pharmacother       Date:  2014-02-12       Impact factor: 3.154

6.  Nonrandomized Intervention Study of Naloxone Coprescription for Primary Care Patients Receiving Long-Term Opioid Therapy for Pain.

Authors:  Phillip O Coffin; Emily Behar; Christopher Rowe; Glenn-Milo Santos; Diana Coffa; Matthew Bald; Eric Vittinghoff
Journal:  Ann Intern Med       Date:  2016-06-28       Impact factor: 25.391

7.  Opioid overdose prevention in a residential care setting: Naloxone education and distribution.

Authors:  Patricia Pade; Patrick Fehling; Sophie Collins; Laura Martin
Journal:  Subst Abus       Date:  2016-04-19       Impact factor: 3.716

8.  Opioid education and nasal naloxone rescue kits in the emergency department.

Authors:  Kristin Dwyer; Alexander Y Walley; Breanne K Langlois; Patricia M Mitchell; Kerrie P Nelson; John Cromwell; Edward Bernstein
Journal:  West J Emerg Med       Date:  2015-04-01

9.  Opioid Overdose Prevention Programs Providing Naloxone to Laypersons - United States, 2014.

Authors:  Eliza Wheeler; T Stephen Jones; Michael K Gilbert; Peter J Davidson
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2015-06-19       Impact factor: 17.586

10.  Why is it so hard to implement change? A qualitative examination of barriers and facilitators to distribution of naloxone for overdose prevention in a safety net environment.

Authors:  Mari-Lynn Drainoni; Elisa A Koppelman; James A Feldman; Alexander Y Walley; Patricia M Mitchell; Jacqueline Ellison; Edward Bernstein
Journal:  BMC Res Notes       Date:  2016-10-18
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  2 in total

1.  Septic Arthritis and the Opioid Epidemic: 1465 Cases of Culture-Positive Native Joint Septic Arthritis From 1990-2018.

Authors:  John J Ross; Kevin L Ard; Narath Carlile
Journal:  Open Forum Infect Dis       Date:  2020-03-12       Impact factor: 3.835

2.  Community Case Study of Naloxone Distribution by Hospital-Based Harm Reduction Program for People Who Use Drugs in New York City.

Authors:  Farah Riazi; Wilma Toribio; Emaun Irani; Terence M Hughes; Zina Huxley-Reicher; Elisa McBratney; Trang Vu; Keith Sigel; Jeffrey J Weiss
Journal:  Front Sociol       Date:  2021-07-07
  2 in total

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