Literature DB >> 2876720

Infusion of vecuronium controlled by a closed-loop system.

J W de Vries, H H Ros, L H Booij.   

Abstract

Closed-loop control of neuromuscular blockade, using a semi-continuous infusion of vecuronium, is described. In 28 patients, the average neuromuscular transmission was between 13 and 17% of control. Requirements for vecuronium averaged 1.1 micrograms kg-1 min-1 (0.8-1.5 micrograms kg-1 min-1), being in the same range as for repeated bolus injections. No side effects were observed. After the infusion was stopped recovery was rapid. Only three patients required induced reversal of blockade.

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Year:  1986        PMID： 2876720     DOI： 10.1093/bja/58.10.1100

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN： 0007-0912            Impact factor:   9.166


  7 in total

1.  In vivo evaluation of a closed loop monitoring strategy for induced paralysis.

Authors:  D Ramakrishna; K Behbehani; K Klein; J Mokhtar; W W von Maltzahn; R C Eberhart; M Dollar
Journal:  J Clin Monit Comput       Date:  1998-08       Impact factor: 2.502

2.  Hierarchical rule-based monitoring and fuzzy logic control for neuromuscular block.

Authors:  J S Shieh; S Z Fan; L W Chang; C C Liu
Journal:  J Clin Monit Comput       Date:  2000       Impact factor: 2.502

3.  Use of a pharmacokinetic-dynamic model for the automatic feedback control of atracurium.

Authors:  H Schwilden; K T Olkkola
Journal:  Eur J Clin Pharmacol       Date:  1991       Impact factor: 2.953

4.  A simple method for monitoring muscular relaxation during continuous infusion of vecuronium.

Authors:  H Nagashima; H D Nguyen; M Conforti; D Duncalf; P L Goldiner; F F Foldes
Journal:  Can J Anaesth       Date:  1988-03       Impact factor: 5.063

5.  A controller for automatic regulation of induced paralysis during surgery.

Authors:  K Behbehani; D Ramakrishna; K Klein
Journal:  Ann Biomed Eng       Date:  1994 Mar-Apr       Impact factor: 3.934

6.  [Feedback control of muscle relaxation with a varying on-off controller using cisatracurium].

Authors:  B Pohl; R Hofmockel; O Simanski; K Wende; B P Lampe
Journal:  Anaesthesist       Date:  2004-01       Impact factor: 1.041

7.  A comparison of computer-controlled versus manual administration of vecuronium in humans.

Authors:  R R Jaklitsch; D R Westenskow; N L Pace; J B Streisand; K A East
Journal:  J Clin Monit       Date:  1987-10
  7 in total

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