| Literature DB >> 28766257 |
Şevket Hakan Üngören1, Şerife Boz2.
Abstract
A multicomponent domino synthesis has been developed for the preparation of 2-aminopyrimidines from β-dicarbonyl compounds, N,N-dimethylformamide dimethyl acetal, and cyanamide. The protocol was used for the regioselective preparation of 4-amide/ester/ketone substituted 2-aminopyrimidines. Twelve 2-aminopyrimidines were isolated in good yields (56-93%).Entities:
Keywords: -Dicarbonyl compound; 2-Aminopyrimidine; Cyanamide; DBU; Domino synthesis; Four-component; MCR
Mesh：
Substances：
Year: 2017 PMID： 28766257 DOI： 10.1007/s11030-017-9770-7
Source DB: PubMed Journal: Mol Divers ISSN： 1381-1991 Impact factor: 2.943