Literature DB >> 2876615

Pathological lesions in mice infected with Thogoto virus, a tick-borne orthomyxovirus.

A R Filipe, M C Peleteiro, T M Monath, E H Calisher.   

Abstract

The RNA structure of tick-borne Thogoto virus was found very closely related to that of the Orthomyxovividae family. Pathological lesions in the lungs, liver and intestine of white mice inoculated with Thogoto virus resemble to those described for influenza virus, however, an important differential characteristic is the high hepatotropism of Thogoto virus. Thogoto virus infection in the liver of mice seems suitable for the study of virus-induced necrotic lesions.

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Year:  1986        PMID： 2876615

Source DB:  PubMed          Journal:  Acta Virol        ISSN： 0001-723X            Impact factor:   1.162


  7 in total

1.  Thogoto virus infection induces sustained type I interferon responses that depend on RIG-I-like helicase signaling of conventional dendritic cells.

Authors:  Georg Kochs; Stefanie Bauer; Carola Vogt; Theresa Frenz; Jürg Tschopp; Ulrich Kalinke; Zoe Waibler
Journal:  J Virol       Date:  2010-09-22       Impact factor: 5.103

2.  Human MxA protein protects mice lacking a functional alpha/beta interferon system against La crosse virus and other lethal viral infections.

Authors:  H P Hefti; M Frese; H Landis; C Di Paolo; A Aguzzi; O Haller; J Pavlovic
Journal:  J Virol       Date:  1999-08       Impact factor: 5.103

3.  Comparative Study of Ten Thogotovirus Isolates and Their Distinct In Vivo Characteristics.

Authors:  Jonas Fuchs; Kevin Lamkiewicz; Larissa Kolesnikova; Martin Hölzer; Manja Marz; Georg Kochs
Journal:  J Virol       Date:  2022-01-12       Impact factor: 6.549

4.  Enhanced virus resistance of transgenic mice expressing the human MxA protein.

Authors:  J Pavlovic; H A Arzet; H P Hefti; M Frese; D Rost; B Ernst; E Kolb; P Staeheli; O Haller
Journal:  J Virol       Date:  1995-07       Impact factor: 5.103

5.  Tick-borne thogoto virus infection in mice is inhibited by the orthomyxovirus resistance gene product Mx1.

Authors:  O Haller; M Frese; D Rost; P A Nuttall; G Kochs
Journal:  J Virol       Date:  1995-04       Impact factor: 5.103

Review 6.  Tick-borne viruses in Europe.

Authors:  Zdenek Hubálek; Ivo Rudolf
Journal:  Parasitol Res       Date:  2012-04-18       Impact factor: 2.383

Review 7.  Modeling Arboviral Infection in Mice Lacking the Interferon Alpha/Beta Receptor.

Authors:  Alejandro Marín-Lopez; Eva Calvo-Pinilla; Sandra Moreno; Sergio Utrilla-Trigo; Aitor Nogales; Alejandro Brun; Erol Fikrig; Javier Ortego
Journal:  Viruses       Date:  2019-01-08       Impact factor: 5.048
  7 in total

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