Literature DB >> 2876061

Neuropeptides in gliomas: identification of somatostatin 14 in a medulloblastoma.

D E Bateman, J R McDermott, R H Perry, R Dimaline, J A Biggins, J A Edwardson.   

Abstract

Forty nine gliomas were analysed for the following neuropeptides: somatostatin (SS), substance P (SP), neurotensin (NT) and vasoactive intestinal polypeptide (VIP) and the pituitary peptide, adrenocorticotrophin (ACTH). A significant amount of authentic SS was found in a medulloblastoma, and low concentrations of SP and NT immunoreactivity in an ependymoma and cerebellar astrocytoma respectively. The majority of the other gliomas did not contain detectable levels of these five neuropeptides. Low levels of neuropeptides were found in some specimens probably due to contamination with cerebral cortex.

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Year:  1986        PMID： 2876061      PMCID： PMC1029017          DOI： 10.1136/jnnp.49.9.1074

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  8 in total

1.  The amino acid sequence of a hypothalamic peptide, neurotensin.

Authors:  R Carraway; S E Leeman
Journal:  J Biol Chem       Date:  1975-03-10       Impact factor: 5.157

2.  Adrenocorticotropin and melanocyte-stimulating hormone in the brain.

Authors:  E Orwoll; J W Kendall; L Lamorena; R McGilvra
Journal:  Endocrinology       Date:  1979-06       Impact factor: 4.736

3.  Vasoactive intestinal polypeptide: abundant immunoreactivity in neural cell lines and normal nervous tissue.

Authors:  S I Said; R N Rosenberg
Journal:  Science       Date:  1976-05-28       Impact factor: 47.728

4.  [Localization of somatostatin in human brain tumors].

Authors:  H Hara; T Moriki; M Miyao; M Hashimoto; T Yamane
Journal:  No To Shinkei       Date:  1983-06

5.  Biosynthesis of substance P in cultured mouse neuroblastoma and rat glioma cells.

Authors:  J Harkins; M Roper; R G Ham; J M Stewart
Journal:  Brain Res       Date:  1978-05-26       Impact factor: 3.252

6.  The cerebellar medulloblastoma and its relationship to primitive neuroectodermal tumors.

Authors:  L B Rorke
Journal:  J Neuropathol Exp Neurol       Date:  1983-01       Impact factor: 3.685

7.  Development and validation of a specific radioimmunoassay for somatostatin in human plasma.

Authors:  E Penman; J A Wass; A Lund; P J Lowry; J Stewart; A M Dawson; G M Besser; L H Rees
Journal:  Ann Clin Biochem       Date:  1979-01       Impact factor: 2.057

8.  Multiple immunoreactive forms of vasoactive intestinal peptide in human colonic mucosa.

Authors:  R Dimaline; G J Dockray
Journal:  Gastroenterology       Date:  1978-09       Impact factor: 22.682
  8 in total
  2 in total

1.  Neuropeptide Y, somatostatin, and cholecystokinin neurone preservation in anaplastic astrocytomas.

Authors:  S Przedborski; S Goldman; S N Schiffmann; G Vierendeels; M Depierreux; M Levivier; J Hildebrand; J J Vanderhaeghen
Journal:  Acta Neuropathol       Date:  1988       Impact factor: 17.088

2.  Effects of the vasoactive intestinal peptide (VIP) and related peptides on glioblastoma cell growth in vitro.

Authors:  Christine Dufes; Céline Alleaume; Alicia Montoni; Jean-Christophe Olivier; Jean-Marc Muller
Journal:  J Mol Neurosci       Date:  2003       Impact factor: 3.444
  2 in total

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