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Literature DB >> 2875796

Ultrastructural localization of calcitonin and somatostatin in C cells of rabbit thyroid.

Abstract

C cells of rabbit thyroid exhibit significant differences in morphology, namely a variable nuclear structure and differences in size and osmophility of secretory granules. An examination of serial sections of these cells was made, using the immunocytochemical PAP or protein A-gold procedures. All C cells, irrespective of their morphology, were found to store both calcitonin and somatostatin in all secretory granules. The physiological role of somatostatin in calcitonin secretion by C cells is discussed.

Entities: Species

Mesh：

Substances：
Somatostatin
Calcitonin

Year: 1986 PMID： 2875796 DOI： 10.1007/bf00218570

Source DB: PubMed Journal: Cell Tissue Res ISSN： 0302-766X Impact factor: 5.249

22 in total

1. Ultrastructural localization of intracellular antigens by the use of protein A-gold complex.

Authors: J Roth; M Bendayan; L Orci
Journal: J Histochem Cytochem Date: 1978-12 Impact factor: 2.479

2. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

Authors: S M Hsu; L Raine; H Fanger
Journal: J Histochem Cytochem Date: 1981-04 Impact factor: 2.479

Ultrastructural localization of calcitonin and somatostatin in C cells of rabbit thyroid.

1. Ultrastructural localization of intracellular antigens by the use of protein A-gold complex.

2. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

Review 3. Amine storage and function in peptide hormone-producing cells.

4. Partial nucleotide sequence of human calcitonin precursor mRNA identifies flanking cryptic peptides.

5. Effect of somatostatin on parathyroid hormone and calcitonin secretion.

6. Studies on in vitro effect of serotonin on calcitonin secretion by rat thyroid C cells.

7. Somatostatin immunoreactive C cells in thyroid glands from various mammalian species.

8. Somatostatin and calcitonin release from perfused dog thyroid lobes. Studies with calcium and pentagastrin.

9. Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products.

10. Ultrastructural localization of calcitonin, somatostatin and serotonin in parafollicular cells of rat thyroid.

1. Changes in parafollicular cells of rats neonatally treated with estradiol.