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Literature DB >> 28757417

miRNAs in B-cell lymphoma: Molecular mechanisms and biomarker potential.

Carla Solé¹, Erika Larrea¹, Giovanni Di Pinto¹, Maitena Tellaetxe¹, Charles Henderson Lawrie².

Abstract

MicroRNAs (miRNAs) are small non-coding RNAs that regulate many human genes including those involved in normal B-cell development. When these miRNAs are aberrantly expressed in B-cells they play key pathogenetic roles in the development and maintenance of B-cell lymphomas and by association may serve as useful biomarkers. In this review, we provide an overview of the importance of miRNAs to B-cell lymphomagenesis, as well as considering their use as biomarkers, and their potential usefulness for the clinic.

Entities: Disease Species

Keywords: B-cell lymphoma; Biomarker; Hodgkin lymphoma; Lymphoma; MicroRNA; Non-Hodgkin lymphoma

Mesh：

Substances：

Year: 2017 PMID： 28757417 DOI： 10.1016/j.canlet.2017.07.020

Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679

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Cited

15 in total

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Journal: Med Sci Monit Date: 2018-08-22

3. MicroRNA-302a/d inhibits the self-renewal capability and cell cycle entry of liver cancer stem cells by targeting the E2F7/AKT axis.

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Journal: J Exp Clin Cancer Res Date: 2018-10-16

4. Identification of Circulating Serum Multi-MicroRNA Signatures in Human DLBCL Models.

Authors: Afshin Beheshti; Kristen Stevenson; Charles Vanderburg; Dashnamoorthy Ravi; J Tyson McDonald; Amanda L Christie; Kay Shigemori; Hallie Jester; David M Weinstock; Andrew M Evens
Journal: Sci Rep Date: 2019-11-20 Impact factor: 4.379

5. The Tumor Suppressive mir-148a Is Epigenetically Inactivated in Classical Hodgkin Lymphoma.

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Journal: Cells Date: 2020-10-14 Impact factor: 6.600

6. Identification of Recurrent Mutations in the microRNA-Binding Sites of B-Cell Lymphoma-Associated Genes in Follicular Lymphoma.

Authors: Erika Larrea; Marta Fernandez-Mercado; José Afonso Guerra-Assunção; Jun Wang; Ibai Goicoechea; Ayman Gaafar; Izaskun Ceberio; Carmen Lobo; Jessica Okosun; Anton J Enright; Jude Fitzgibbon; Charles H Lawrie
Journal: Int J Mol Sci Date: 2020-11-20 Impact factor: 5.923

7. MYC-related microRNAs signatures in non-Hodgkin B-cell lymphomas and their relationships with core cellular pathways.

Authors: Giorgio Malpeli; Stefano Barbi; Gabriele Tosadori; Corinna Greco; Simonetta Zupo; Serena Pedron; Matteo Brunelli; Anna Bertolaso; Maria Teresa Scupoli; Mauro Krampera; Paul Takam Kamga; Carlo Maria Croce; George Adrian Calin; Aldo Scarpa; Alberto Zamò
Journal: Oncotarget Date: 2018-07-03