Xiang-Long Meng1,2, Jun-Nan Ma1,2, Xiao-Hui Guo3, Bing-Chen Liu2, Nan-Nan Cui4, Kun Li2, Shuo-Sheng Zhang5. 1. Department of Herbology, College of Oriental Medicine, Dongguk University, Gyeongju, 780-714, Republic of Korea. 2. Institute of Pharmaceutical & Food Engineering, Shanxi University of Traditional Chinese Medicine, Jinzhong, Shanxi Province, 030619, China. 3. Institute of Coal Chemistry, Chinese Academy of Sciences, Key Laboratory of Carbon Materials, Taiyuan, 030024, China. 4. Hubei University of Medicine, Shiyan, Hubei Province, 442000, China. 5. Institute of Pharmaceutical & Food Engineering, Shanxi University of Traditional Chinese Medicine, Jinzhong, Shanxi Province, 030619, China. zhangshuosheng@aliyun.com.
Abstract
OBJECTIVE: To determine the pyrolysis characteristics of calcined and processed calamine, qualitatively and quantitatively compare the contents of related elements, morphology and functional groups of the pyrolysis products dried at different heating temperatures and explore the critical temperature and the optimal drying temperature for the process of calamine with Huanglian Decoction (HLD, ) and San Huang Decoction (SHD, ). METHODS: Pyrolysis products were prepared by programmable and constantly heating the calcined and processed calamine to or at different heating temperatures. Thermogravimetry (TG) was used to test their pyrolysis characteristics. Fourier transform infrared spectroscopy and scanning electron microscopeenergy dispersive spectrometer were used to determine their morphology, functional groups and element contents. Page model was used to investigate the constant drying kinetics of processed calamine. RESULTS: The adding of HLD or SHD to calcined calamine (CC) can slow its weight loss in drying pyrolysis process. The temperature ranges where HLD and SHD can affect its weight loss were 65-150 °C and 74-180 °C, respectively. The drying temperature was optimized as 90 °C. The drying kinetic for the processed calamine fits Page model shows good linearity. CONCLUSIONS: Conclusions: The critical temperature and the optimal drying temperature where HLD and SHD can affect the weight loss rate in the process of calamine were explored using the theories and methods of both biophysical chemistry and processing of Chinese materia medica. This work provides a good example for the study of the process of other Chinese medicines using modern analytical techniques.
OBJECTIVE: To determine the pyrolysis characteristics of calcined and processed calamine, qualitatively and quantitatively compare the contents of related elements, morphology and functional groups of the pyrolysis products dried at different heating temperatures and explore the critical temperature and the optimal drying temperature for the process of calamine with Huanglian Decoction (HLD, ) and San Huang Decoction (SHD, ). METHODS: Pyrolysis products were prepared by programmable and constantly heating the calcined and processed calamine to or at different heating temperatures. Thermogravimetry (TG) was used to test their pyrolysis characteristics. Fourier transform infrared spectroscopy and scanning electron microscopeenergy dispersive spectrometer were used to determine their morphology, functional groups and element contents. Page model was used to investigate the constant drying kinetics of processed calamine. RESULTS: The adding of HLD or SHD to calcined calamine (CC) can slow its weight loss in drying pyrolysis process. The temperature ranges where HLD and SHD can affect its weight loss were 65-150 °C and 74-180 °C, respectively. The drying temperature was optimized as 90 °C. The drying kinetic for the processed calaminefits Page model shows good linearity. CONCLUSIONS: Conclusions: The critical temperature and the optimal drying temperature where HLD and SHD can affect the weight loss rate in the process of calamine were explored using the theories and methods of both biophysical chemistry and processing of Chinese materia medica. This work provides a good example for the study of the process of other Chinese medicines using modern analytical techniques.
Entities:
Keywords:
calcined calamine; fourier transformation infrared spectrometry; processed Calamine; processing of Chinese materia medica; scanning electron microscope-energy dispersive spectrometer; thermogravimetry
Authors: Jinmin Shi; Yifan Yang; Xinxin Zhou; Lijun Zhao; Xiaohua Li; Abdullah Yusuf; Mohaddeseh S M Z Hosseini; Fatemeh Sefidkon; Xuebo Hu Journal: Front Pharmacol Date: 2022-09-14 Impact factor: 5.988