İlkay Er1, Ayla Günlemez1, Zeynep Seda Uyan2, Metin Aydoğan3, Meral Oruç1, Olcay Işık1, Ayşe Engin Arısoy1, Canan Baydemir4, Ayşe Sevim Gökalp1. 1. Department of Pediatrics, Division of Neonatology, Kocaeli University School of Medicine, Kocaeli, Turkey. 2. Department of Pediatrics, Division of Pediatric Chest Diseases, Kocaeli University School of Medicine, Kocaeli, Turkey. 3. Department of Pediatrics, Division of Pediatric Immunology and Allergy, Kocaeli University School of Medicine, Kocaeli, Turkey. 4. Department of Biostatistics, Kocaeli University School of Medicine, Kocaeli, Turkey.
Abstract
AIM: The aim of this study was to evaluate the pulmonary functions of preschool children born late-preterm. MATERIAL AND METHODS: Children aged between 3-7 years who were born at 340/7-366/7 weeks' gestation represented the target sample. Patients with a diagnosis of congenital cardiac, pulmonary and/or muscle diseases were excluded. Respiratory symptoms were evaluated using the modified asthma predictive index and International Study of Asthma and Allergies in Childhood criteria for children aged under and over 6 years, respectively. Skin prick tests were performed. Age-matched healthy controls were chosen according to the criteria proposed by the American Thoracic Society. Lung functions were evaluated using impulse oscillometry study in both groups. Data were recorded in the SPSS program. RESULTS: A total of 139 late-preterms and 75 healthy controls participated in the study. The mean gestational week of the late-preterms was 35.3±0.9 weeks. The main admission diagnosis to neonatal intensive care unit was respiratory distress. In the postdischarge period, 54.1% were hospitalized for pulmonary infections at least once, and 57.8% were passive smoking currently. Aeroallergen sensitivity was detected as 25.8% in the late-preterm group; 34.5% and 15.1% were diagnosed as having asthma and non-asthmatic atopy, respectively. Impulse oscillometry study parameters of R5, R10, and Z5 were higher and X10 and X15 were lower in late-preterms than in controls (p<0.05). Late-preterms with and without respiratory distress in the postnatal period revealed no statistical differences for any parameters. CONCLUSIONS: Our findings suggest that presence of increased peripheral airway resistance in late-preterms as compared to term-born controls.
AIM: The aim of this study was to evaluate the pulmonary functions of preschool children born late-preterm. MATERIAL AND METHODS:Children aged between 3-7 years who were born at 340/7-366/7 weeks' gestation represented the target sample. Patients with a diagnosis of congenital cardiac, pulmonary and/or muscle diseases were excluded. Respiratory symptoms were evaluated using the modified asthma predictive index and International Study of Asthma and Allergies in Childhood criteria for children aged under and over 6 years, respectively. Skin prick tests were performed. Age-matched healthy controls were chosen according to the criteria proposed by the American Thoracic Society. Lung functions were evaluated using impulse oscillometry study in both groups. Data were recorded in the SPSS program. RESULTS: A total of 139 late-preterms and 75 healthy controls participated in the study. The mean gestational week of the late-preterms was 35.3±0.9 weeks. The main admission diagnosis to neonatal intensive care unit was respiratory distress. In the postdischarge period, 54.1% were hospitalized for pulmonary infections at least once, and 57.8% were passive smoking currently. Aeroallergen sensitivity was detected as 25.8% in the late-preterm group; 34.5% and 15.1% were diagnosed as having asthma and non-asthmatic atopy, respectively. Impulse oscillometry study parameters of R5, R10, and Z5 were higher and X10 and X15 were lower in late-preterms than in controls (p<0.05). Late-preterms with and without respiratory distress in the postnatal period revealed no statistical differences for any parameters. CONCLUSIONS: Our findings suggest that presence of increased peripheral airway resistance in late-preterms as compared to term-born controls.
Authors: Luciana Friedrich; Renato T Stein; Paulo M C Pitrez; Andrea L Corso; Marcus H Jones Journal: Am J Respir Crit Care Med Date: 2005-12-01 Impact factor: 21.405
Authors: Luciana Friedrich; Paulo M C Pitrez; Renato T Stein; Marcelo Goldani; Robert Tepper; Marcus H Jones Journal: Am J Respir Crit Care Med Date: 2007-09-20 Impact factor: 21.405
Authors: T Todisco; F M de Benedictis; L Iannacci; S Baglioni; A Eslami; E Todisco; M Dottorini Journal: Eur J Pediatr Date: 1993-01 Impact factor: 3.183
Authors: Timothy S Chang; Robert F Lemanske; Theresa W Guilbert; James E Gern; Michael H Coen; Michael D Evans; Ronald E Gangnon; C David Page; Daniel J Jackson Journal: J Allergy Clin Immunol Pract Date: 2013-03