Literature DB >> 28746269

Transversus Abdominis Plane Blocks with Single-Dose Liposomal Bupivacaine in Conjunction with a Nonnarcotic Pain Regimen Help Reduce Length of Stay following Abdominally Based Microsurgical Breast Reconstruction.

Eric M Jablonka1,2, Andreas M Lamelas1,2, Julie N Kim1,2, Bianca Molina1,2, Nathan Molina1,2, Michelle Okwali1,2, William Samson1,2, Mark R Sultan1,2, Joseph H Dayan1,2, Mark L Smith1,2.   

Abstract

BACKGROUND: Side effects associated with use of postoperative narcotics for pain control can delay recovery after abdominally based microsurgical breast reconstruction. The authors evaluated a nonnarcotic pain control regimen in conjunction with bilateral transversus abdominis plane blocks on facilitating early hospital discharge.
METHODS: A retrospective analysis was performed of consecutive patients who underwent breast reconstruction using abdominally based free flaps, with or without being included in a nonnarcotic protocol using intraoperative transversus abdominis plane blockade. During this period, the use of locoregional analgesia evolved from none (control), to continuous bupivacaine infusion transversus abdominis plane and catheters, to single-dose transversus abdominis plane blockade with liposomal bupivacaine solution. Demographic factors, length of stay, inpatient opioid consumption, and complications were reported for all three groups.
RESULTS: One hundred twenty-eight consecutive patients (182 flaps) were identified. Forty patients (62 flaps) were in the infusion-liposomal bupivacaine group, 48 (66 flaps) were in the single-dose blockade-catheter group, and 40 (54 flaps) were in the control group. The infusion-liposomal bupivacaine patients had a significantly shorter hospital stay compared with the single-dose blockade-catheter group (2.65 ± 0.66 versus 3.52 ± 0.92 days; p < 0.0001) and the control group (2.65 ± 0.66 versus 4.05 ± 1.26 days; p < 0.0001). There was no significant difference in flap loss or major complications among groups.
CONCLUSIONS: When used as part of a nonnarcotic postoperative pain regimen, transversus abdominis plane blocks performed with single injections of liposomal bupivacaine help facilitate early hospital discharge after abdominally based microsurgical breast reconstruction. A trend toward consistent discharge by postoperative day 2 was seen. This could result in significant cost savings for health care systems. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.

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Year:  2017        PMID: 28746269      PMCID: PMC9074889          DOI: 10.1097/PRS.0000000000003508

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   5.169


  45 in total

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4.  Ultrasound-guided bilateral transversus abdominis plane block for postoperative analgesia after breast reconstruction by DIEP flap.

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Review 5.  The value of "multimodal" or "balanced analgesia" in postoperative pain treatment.

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8.  Factors associated with anastomotic failure after microvascular reconstruction of the breast.

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9.  The transversus abdominis plane block provides effective postoperative analgesia in patients undergoing total abdominal hysterectomy.

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Review 3.  Practical Review of Abdominal and Breast Regional Analgesia for Plastic Surgeons: Evidence and Techniques.

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4.  Reducing the pain: A cost-effectiveness analysis of transversus abdominis plane block using liposomal bupivacaine for outpatient laparoscopic ventral hernia repair.

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6.  Transversus abdominus plane blocks do not reduce rates of postoperative prolonged opioid use following abdominally based autologous breast reconstruction: a nationwide longitudinal analysis.

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7.  Examining Length of Hospital Stay after Microsurgical Breast Reconstruction: Evaluation in a Case-Control Study.

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Review 10.  Perioperative Blocks for Decreasing Postoperative Narcotics in Breast Reconstruction.

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