Literature DB >> 28744435

Management of malaria in children with fever in rural Sierra Leone in relation to the 2014-2015 Ebola outbreak.

F L Moses1, D Tamang2, O Denisiuk3, U Dumbuya1, K Hann4, R Zachariah5.   

Abstract

Setting: Sixty-eight primary health facilities, Koinadugu District, rural Sierra Leone.
Objectives: Sierra Leone, a country with one of the highest burdens of malaria, was severely affected by the 2014-2015 Ebola virus disease outbreak. In under-five children, we compared trends in the completeness of malaria reports sent to the district office during the pre-Ebola, Ebola and post-Ebola periods, including the number of children with reported fever, malaria diagnostic testing performed and treatment for malaria initiated with artemisinin-based combination therapy (ACT). Design: A cross-sectional study.
Results: Of 1904 expected malaria reports, 1289 (68%) were received. Completeness of reporting was 61% pre-Ebola, increased to 88% during the outbreak and dropped to 44% post-Ebola (P = 0.003). Total malaria testing (n = 105 558) exceeded the number of fever cases (n = 105 320). Pre-Ebola, 75% (n = 43 245) of all reported fever cases received malaria treatment, dropping to 34% (n = 50 453) during the Ebola outbreak. Of 36 804 confirmed malaria cases during Ebola, 17 438 (47%) were treated, significantly fewer than in the pre-Ebola period (96%, P < 0.001). Of the fever cases, 95% in both the pre- and post-Ebola periods received ACT, a rate that increased to 99% during the Ebola outbreak.
Conclusion: Pre-existing gaps in malaria reporting worsened after the Ebola outbreak. Reassuringly, malaria testing matched fever cases, although only half of all confirmed cases received treatment during the outbreak, possibly explained by outbreak-related operational difficulties. These findings could be useful to guide health systems strengthening and recovery.

Entities:  

Keywords:  SORT IT; artemisinin combination therapy; health systems strengthening; operational research; rapid diagnostic test

Year:  2017        PMID: 28744435      PMCID: PMC5515559          DOI: 10.5588/pha.16.0085

Source DB:  PubMed          Journal:  Public Health Action        ISSN: 2220-8372


  13 in total

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Authors:  O J Gadabu; C V Munthali; R Zachariah; S Gudmund-Hinderaker; A Jahn; H Twea; A Gondwe; S Mumba; M Lungu; K Malisita; E Mhango; S D Makombe; L Tenthani; L Mwalwanda; C Moyo; G P Douglas; Z L Lewis; F Chimbwandira
Journal:  Public Health Action       Date:  2011-09-21

2.  The WHO clinical case definition for suspected cases of Ebola virus disease arriving at Ebola holding units: reason to worry?

Authors:  Rony Zachariah; Anthony D Harries
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3.  Ebola in Africa: beyond epidemics, reproductive health in crisis.

Authors:  Alexandre Delamou; Rachel M Hammonds; Séverine Caluwaerts; Bettina Utz; Thérèse Delvaux
Journal:  Lancet       Date:  2014-12-13       Impact factor: 79.321

4.  Ebola in west Africa: from disease outbreak to humanitarian crisis.

Authors:  Peter Piot; Jean-Jacques Muyembe; W John Edmunds
Journal:  Lancet Infect Dis       Date:  2014-10-01       Impact factor: 25.071

5.  Emergence of Zaire Ebola virus disease in Guinea.

Authors:  Sylvain Baize; Delphine Pannetier; Lisa Oestereich; Toni Rieger; Lamine Koivogui; N'Faly Magassouba; Barrè Soropogui; Mamadou Saliou Sow; Sakoba Keïta; Hilde De Clerck; Amanda Tiffany; Gemma Dominguez; Mathieu Loua; Alexis Traoré; Moussa Kolié; Emmanuel Roland Malano; Emmanuel Heleze; Anne Bocquin; Stephane Mély; Hervé Raoul; Valérie Caro; Dániel Cadar; Martin Gabriel; Meike Pahlmann; Dennis Tappe; Jonas Schmidt-Chanasit; Benido Impouma; Abdoul Karim Diallo; Pierre Formenty; Michel Van Herp; Stephan Günther
Journal:  N Engl J Med       Date:  2014-04-16       Impact factor: 91.245

6.  Impact of the Ebola epidemic on general and HIV care in Macenta, Forest Guinea, 2014.

Authors:  David Leuenberger; Jean Hebelamou; Stefan Strahm; Nathalie De Rekeneire; Eric Balestre; Gilles Wandeler; François Dabis
Journal:  AIDS       Date:  2015-09-10       Impact factor: 4.177

7.  ReEBOV Antigen Rapid Test kit for point-of-care and laboratory-based testing for Ebola virus disease: a field validation study.

Authors:  Mara Jana Broadhurst; John Daniel Kelly; Ann Miller; Amanda Semper; Daniel Bailey; Elisabetta Groppelli; Andrew Simpson; Tim Brooks; Susan Hula; Wilfred Nyoni; Alhaji B Sankoh; Santigi Kanu; Alhaji Jalloh; Quy Ton; Nicholas Sarchet; Peter George; Mark D Perkins; Betsy Wonderly; Megan Murray; Nira R Pollock
Journal:  Lancet       Date:  2015-06-25       Impact factor: 79.321

8.  Ebola outbreak in rural West Africa: epidemiology, clinical features and outcomes.

Authors:  Silvia Dallatomasina; Rosa Crestani; James Sylvester Squire; Hilde Declerk; Grazia Marta Caleo; Anja Wolz; Kathryn Stinson; Gabriela Patten; Raphael Brechard; Osman Bamba-Moi Gbabai; Armand Spreicher; Michel Van Herp; Rony Zachariah
Journal:  Trop Med Int Health       Date:  2015-02-03       Impact factor: 2.622

9.  Effect of the Ebola-virus-disease epidemic on malaria case management in Guinea, 2014: a cross-sectional survey of health facilities.

Authors:  Mateusz M Plucinski; Timothée Guilavogui; Sidibe Sidikiba; Nouman Diakité; Souleymane Diakité; Mohamed Dioubaté; Ibrahima Bah; Ian Hennessee; Jessica K Butts; Eric S Halsey; Peter D McElroy; S Patrick Kachur; Jamila Aboulhab; Richard James; Moussa Keita
Journal:  Lancet Infect Dis       Date:  2015-06-23       Impact factor: 25.071

10.  Electronic medical record systems are associated with appropriate placement of HIV patients on antiretroviral therapy in rural health facilities in Kenya: a retrospective pre-post study.

Authors:  Tom Oluoch; Abraham Katana; Victor Ssempijja; Daniel Kwaro; Patrick Langat; Davies Kimanga; Nicky Okeyo; Ameen Abu-Hanna; Nicolette de Keizer
Journal:  J Am Med Inform Assoc       Date:  2014-06-09       Impact factor: 4.497

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  4 in total

1.  What was the effect of the West African Ebola outbreak on health programme performance, and did programmes recover?

Authors:  Tom Decroo; Gabriel Fitzpatrick; Jackson Amone
Journal:  Public Health Action       Date:  2017-06-21

2.  Factors associated with access and adherence to artemisinin-based combination therapy (ACT) for children under five: a secondary analysis of a national survey in Sierra Leone.

Authors:  Kristin Banek; Emily L Webb; Emily Bostick Doogue; Samuel Juana Smith; Daniel Chandramohan; Sarah G Staedke
Journal:  Malar J       Date:  2021-01-21       Impact factor: 2.979

Review 3.  The impact of the Ebola epidemics on children's rights: a scoping review.

Authors:  Irene Lunghi; Awa Babington-Ashaye; Jean-Dominique Vassalli; Yvon Heller; Pierre-André Michaud; Didier Wernli; Olivia Heller; Antoine Flahault; Stéphanie Dagron
Journal:  Glob Health Action       Date:  2022-12-31       Impact factor: 2.996

4.  Adherence to treatment with artemether-lumefantrine or amodiaquine-artesunate for uncomplicated malaria in children in Sierra Leone: a randomized trial.

Authors:  Kristin Banek; Emily L Webb; Samuel Juana Smith; Daniel Chandramohan; Sarah G Staedke
Journal:  Malar J       Date:  2018-06-04       Impact factor: 2.979

  4 in total

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