Literature DB >> 28742335

5-Formylcytosine Yields DNA-Protein Cross-Links in Nucleosome Core Particles.

Fengchao Li1, Yingqian Zhang1, Jing Bai1, Marc M Greenberg2, Zhen Xi1,3, Chuanzheng Zhou1,3.   

Abstract

In situ generation of 5-formylcytosine (5fC) in nucleosome core particles (NCPs) reveals that 5fC leads to essential DNA-protein cross-links (DPCs). Mechanistic studies using chemical models and mutated histones demonstrate that DPCs form reversibly between the formyl function of 5fC and primary amines on histones. These results suggest that DPC formation from 5fC in chromatin occurs in addition to its role in DNA demethylation.

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Year:  2017        PMID： 28742335      PMCID： PMC5649621          DOI： 10.1021/jacs.7b05495

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  29 in total

1.  Cleavage by calicheamicin gamma 1I of DNA in a nucleosome formed on the 5S RNA gene of Xenopus borealis.

Authors:  P N Kuduvalli; C A Townsend; T D Tullius
Journal:  Biochemistry       Date:  1995-03-28       Impact factor: 3.162

2.  Mechanistic studies on histone catalyzed cleavage of apyrimidinic/apurinic sites in nucleosome core particles.

Authors:  Chuanzheng Zhou; Jonathan T Sczepanski; Marc M Greenberg
Journal:  J Am Chem Soc       Date:  2012-09-28       Impact factor: 15.419

3.  Syntheses of 5-formyl- and 5-carboxyl-dC containing DNA oligos as potential oxidation products of 5-hydroxymethylcytosine in DNA.

Authors:  Qing Dai; Chuan He
Journal:  Org Lett       Date:  2011-06-07       Impact factor: 6.005

Review 4.  TET enzymes, TDG and the dynamics of DNA demethylation.

Authors:  Rahul M Kohli; Yi Zhang
Journal:  Nature       Date:  2013-10-24       Impact factor: 49.962

5.  Histone-catalyzed cleavage of nucleosomal DNA containing 2-deoxyribonolactone.

Authors:  Chuanzheng Zhou; Marc M Greenberg
Journal:  J Am Chem Soc       Date:  2012-05-02       Impact factor: 15.419

6.  5-Formylcytosine Could Be a Semipermanent Base in Specific Genome Sites.

Authors:  Meng Su; Angie Kirchner; Samuele Stazzoni; Markus Müller; Mirko Wagner; Arne Schröder; Thomas Carell
Journal:  Angew Chem Int Ed Engl       Date:  2016-08-25       Impact factor: 15.336

7.  Distributive Processing by the Iron(II)/α-Ketoglutarate-Dependent Catalytic Domains of the TET Enzymes Is Consistent with Epigenetic Roles for Oxidized 5-Methylcytosine Bases.

Authors:  Esta Tamanaha; Shengxi Guan; Katherine Marks; Lana Saleh
Journal:  J Am Chem Soc       Date:  2016-07-19       Impact factor: 15.419

8.  Thiazolidine formation as a general and site-specific conjugation method for synthetic peptides and proteins.

Authors:  L Zhang; J P Tam
Journal:  Anal Biochem       Date:  1996-01-01       Impact factor: 3.365

9.  5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription.

Authors:  Matthew W Kellinger; Chun-Xiao Song; Jenny Chong; Xing-Yu Lu; Chuan He; Dong Wang
Journal:  Nat Struct Mol Biol       Date:  2012-07-22       Impact factor: 15.369

10.  5-Formylcytosine alters the structure of the DNA double helix.

Authors:  Eun-Ang Raiber; Pierre Murat; Dimitri Y Chirgadze; Dario Beraldi; Ben F Luisi; Shankar Balasubramanian
Journal:  Nat Struct Mol Biol       Date:  2014-12-15       Impact factor: 15.369
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  27 in total

1.  Error-prone replication of a 5-formylcytosine-mediated DNA-peptide cross-link in human cells.

Authors:  Spandana Naldiga; Shaofei Ji; Jenna Thomforde; Claudia M Nicolae; Marietta Lee; Zhongtao Zhang; George-Lucian Moldovan; Natalia Y Tretyakova; Ashis K Basu
Journal:  J Biol Chem       Date:  2019-05-28       Impact factor: 5.157

Review 2.  Protein Interactions at Oxidized 5-Methylcytosine Bases.

Authors:  Gerd P Pfeifer; Piroska E Szabó; Jikui Song
Journal:  J Mol Biol       Date:  2019-08-08       Impact factor: 5.469

3.  Oxidation of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Leads to Substantial DNA-Histone Cross-Links within Nucleosome Core Particles.

Authors:  Jing Bai; Yingqian Zhang; Zhen Xi; Marc M Greenberg; Chuanzheng Zhou
Journal:  Chem Res Toxicol       Date:  2018-11-19       Impact factor: 3.739

4.  Transcriptional Bypass of DNA-Protein and DNA-Peptide Conjugates by T7 RNA Polymerase.

Authors:  Shaofei Ji; Jenna Thomforde; Colette Rogers; Iwen Fu; Suse Broyde; Natalia Y Tretyakova
Journal:  ACS Chem Biol       Date:  2019-10-21       Impact factor: 5.100

5.  5-Formylcytosine-induced DNA-peptide cross-links reduce transcription efficiency, but do not cause transcription errors in human cells.

Authors:  Shaofei Ji; Daeyoon Park; Konstantin Kropachev; Marina Kolbanovskiy; Iwen Fu; Suse Broyde; Maram Essawy; Nicholas E Geacintov; Natalia Y Tretyakova
Journal:  J Biol Chem       Date:  2019-10-09       Impact factor: 5.157

6.  Reactivity of the Major Product of C5'-Oxidative DNA Damage in Nucleosome Core Particles.

Authors:  Anup Rana; Kun Yang; Marc M Greenberg
Journal:  Chembiochem       Date:  2019-01-10       Impact factor: 3.164

7.  Reversible DNA-Protein Cross-Linking at Epigenetic DNA Marks.

Authors:  Shaofei Ji; Hongzhao Shao; Qiyuan Han; Christopher L Seiler; Natalia Y Tretyakova
Journal:  Angew Chem Int Ed Engl       Date:  2017-10-06       Impact factor: 15.336

8.  Rotational Effects within Nucleosome Core Particles on Abasic Site Reactivity.

Authors:  Ruixiang Wang; Kun Yang; Samya Banerjee; Marc M Greenberg
Journal:  Biochemistry       Date:  2018-06-12       Impact factor: 3.162

9.  Histone Tail Sequences Balance Their Role in Genetic Regulation and the Need To Protect DNA against Destruction in Nucleosome Core Particles Containing Abasic Sites.

Authors:  Kun Yang; Marc M Greenberg
Journal:  Chembiochem       Date:  2018-11-15       Impact factor: 3.164

10.  Participation of Histones in DNA Damage and Repair within Nucleosome Core Particles: Mechanism and Applications.

Authors:  Mengtian Ren; Marc M Greenberg; Chuanzheng Zhou
Journal:  Acc Chem Res       Date:  2022-03-10       Impact factor: 22.384
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