Literature DB >> 2874223

Metabolic basis of adverse drug reactions.

B K Park.   

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Year:  1986        PMID： 2874223      PMCID： PMC5371054     

Source DB:  PubMed          Journal:  J R Coll Physicians Lond        ISSN： 0035-8819


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  10 in total

Review 1.  Idiosyncratic drug reactions: a mechanistic evaluation of risk factors.

Authors:  B K Park; M Pirmohamed; N R Kitteringham
Journal:  Br J Clin Pharmacol       Date:  1992-11       Impact factor: 4.335

2.  In response to Vriesendorp et al. prediction of normal tissue damage by cancer chemotherapy.

Authors:  J A Green
Journal:  Cancer Chemother Pharmacol       Date:  1988       Impact factor: 3.333

3.  Bioactivation of dapsone to a cytotoxic metabolite: in vitro use of a novel two compartment system which contains human tissues.

Authors:  R J Riley; P Roberts; M D Coleman; N R Kitteringham; B K Park
Journal:  Br J Clin Pharmacol       Date:  1990-09       Impact factor: 4.335

4.  Detection of an autoantibody directed against human liver microsomal protein in a patient with carbamazepine hypersensitivity.

Authors:  M Pirmohamed; N R Kitteringham; A M Breckenridge; B K Park
Journal:  Br J Clin Pharmacol       Date:  1992-02       Impact factor: 4.335

5.  Metabolism of ciamexon by human liver microsomes: an investigation into the formation of stable, chemically reactive and cytotoxic metabolites.

Authors:  M D Tingle; B K Park
Journal:  Br J Clin Pharmacol       Date:  1990-05       Impact factor: 4.335

6.  Carbamazepine-hypersensitivity: assessment of clinical and in vitro chemical cross-reactivity with phenytoin and oxcarbazepine.

Authors:  M Pirmohamed; A Graham; P Roberts; D Smith; D Chadwick; A M Breckenridge; B K Park
Journal:  Br J Clin Pharmacol       Date:  1991-12       Impact factor: 4.335

7.  Inhibition of CYP2D6 activity by treatment with propranolol and the role of 4-hydroxy propranolol.

Authors:  K Rowland; W W Yeo; S W Ellis; I G Chadwick; I Haq; M S Lennard; P R Jackson; L E Ramsay; G T Tucker
Journal:  Br J Clin Pharmacol       Date:  1994-07       Impact factor: 4.335

Review 8.  The role of active metabolites in drug toxicity.

Authors:  M Pirmohamed; N R Kitteringham; B K Park
Journal:  Drug Saf       Date:  1994-08       Impact factor: 5.606

9.  A stereochemical investigation of the cytotoxicity of mianserin metabolites in vitro.

Authors:  R J Riley; C Lambert; N R Kitteringham; B K Park
Journal:  Br J Clin Pharmacol       Date:  1989-06       Impact factor: 4.335

10.  An in vitro study of the microsomal metabolism and cellular toxicity of phenytoin, sorbinil and mianserin.

Authors:  R J Riley; J L Maggs; C Lambert; N R Kitteringham; B K Park
Journal:  Br J Clin Pharmacol       Date:  1988-11       Impact factor: 4.335
  10 in total

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