| Literature DB >> 28741531 |
Bushra Ateeq1, Vipul Bhatia2, Sakshi Goel2.
Abstract
Recent molecular characterization of prostate cancer (PCa) identified novel genetic aberrations and disease subtypes. The frequencies of molecular aberrations show racial disparity. Clinical strategies and targeted therapies embracing these racial differences are required. Here we discuss ethnic differences in genetic alterations and their impact on the susceptibility, progression, and treatment of prostate cancer.Entities:
Keywords: 8q24 locus; SPINK1; SPOP; TMPRSS2–ERG; prostate cancer
Mesh:
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Year: 2016 PMID: 28741531 PMCID: PMC6485634 DOI: 10.1016/j.trecan.2016.01.005
Source DB: PubMed Journal: Trends Cancer ISSN: 2405-8025