Literature DB >> 28735612

Cutaneous Glucocorticoidogenesis and Cortisol Signaling Are Defective in Psoriasis.

Andrzej T Slominski1, Anna A Brożyna2, Robert C Tuckey3.   

Abstract

Hannen et al. report that cutaneous glucocorticoidogenesis and expression of glucocorticoid receptors are inhibited in psoriatic skin. These findings substantiate the previous concept that deficient feedback of local proopiomelanocortin and glucocorticoids on cutaneous immunity contributes to inflammatory and autoimmune dermatoses. Restoration of efficient endogenous glucocorticoid signaling represents a realistic goal in treating psoriasis.
Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

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Year:  2017        PMID： 28735612      PMCID： PMC5560585          DOI： 10.1016/j.jid.2017.04.004

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  15 in total

Review 1.  The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions.

Authors:  Andrzej T Slominski; Tae-Kang Kim; Wei Li; Ae-Kyung Yi; Arnold Postlethwaite; Robert C Tuckey
Journal:  J Steroid Biochem Mol Biol       Date:  2013-10-28       Impact factor: 4.292

Review 2.  The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders.

Authors:  Walter L Miller; Richard J Auchus
Journal:  Endocr Rev       Date:  2010-11-04       Impact factor: 19.871

3.  ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin.

Authors:  A Slominski; G Ermak; M Mihm
Journal:  J Clin Endocrinol Metab       Date:  1996-07       Impact factor: 5.958

Review 4.  Progesterone synthesis by the human placenta.

Authors:  Robert C Tuckey
Journal:  Placenta       Date:  2005-04       Impact factor: 3.481

5.  Dysfunctional Skin-Derived Glucocorticoid Synthesis Is a Pathogenic Mechanism of Psoriasis.

Authors:  Rosalind Hannen; Chinedu Udeh-Momoh; James Upton; Michael Wright; Anthony Michael; Abha Gulati; Shefali Rajpopat; Nicky Clayton; David Halsall; Jacky Burrin; Roderick Flower; Lisa Sevilla; Victor Latorre; James Frame; Stafford Lightman; Paloma Perez; Michael Philpott
Journal:  J Invest Dermatol       Date:  2017-03-28       Impact factor: 8.551

Review 6.  On the role of skin in the regulation of local and systemic steroidogenic activities.

Authors:  Andrzej T Slominski; Pulak R Manna; Robert C Tuckey
Journal:  Steroids       Date:  2015-05-16       Impact factor: 2.668

7.  A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin.

Authors:  Andrzej Slominski; Jordan Zjawiony; Jacobo Wortsman; Igor Semak; Jeremy Stewart; Alexander Pisarchik; Trevor Sweatman; Josep Marcos; Chuck Dunbar; Robert C Tuckey
Journal:  Eur J Biochem       Date:  2004-11

8.  Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice.

Authors:  Karin M Aberg; Katherine A Radek; Eung-Ho Choi; Dong-Kun Kim; Marianne Demerjian; Melanie Hupe; Joseph Kerbleski; Richard L Gallo; Tomas Ganz; Theodora Mauro; Kenneth R Feingold; Peter M Elias
Journal:  J Clin Invest       Date:  2007-11       Impact factor: 14.808

9.  Ultraviolet radiation regulates cortisol activity in a waveband-dependent manner in human skin ex vivo.

Authors:  C Skobowiat; R M Sayre; J C Dowdy; A T Slominski
Journal:  Br J Dermatol       Date:  2013-01-31       Impact factor: 9.302

Review 10.  Key role of CRF in the skin stress response system.

Authors:  Andrzej T Slominski; Michal A Zmijewski; Blazej Zbytek; Desmond J Tobin; Theoharis C Theoharides; Jean Rivier
Journal:  Endocr Rev       Date:  2013-08-12       Impact factor: 19.871
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  12 in total

Review 1.  How UV Light Touches the Brain and Endocrine System Through Skin, and Why.

Authors:  Andrzej T Slominski; Michal A Zmijewski; Przemyslaw M Plonka; Jerzy P Szaflarski; Ralf Paus
Journal:  Endocrinology       Date:  2018-05-01       Impact factor: 4.736

2.  Adrenocorticotropin/cortisol ratio - a marker of psoriasis severity.

Authors:  Radosław Pietrzak; Paweł Rykowski; Anna Pasierb; Zbigniew Bartoszewicz; Małgorzata Stakun; Małgorzata Rykowska; Katarzyna Karoń; Lidia Rudnicka; Joanna Czuwara
Journal:  Postepy Dermatol Alergol       Date:  2019-04-09       Impact factor: 1.837

3.  The significance of CYP11A1 expression in skin physiology and pathology.

Authors:  R M Slominski; C Raman; C Elmets; A M Jetten; A T Slominski; R C Tuckey
Journal:  Mol Cell Endocrinol       Date:  2021-03-12       Impact factor: 4.369

4.  Staphylococcus aureus enterotoxins modulate IL-22-secreting cells in adults with atopic dermatitis.

Authors:  Raquel Leao Orfali; Luanda Mara da Silva Oliveira; Josenilson Feitosa de Lima; Gabriel Costa de Carvalho; Yasmim Alefe Leuzzi Ramos; Natalli Zanete Pereira; Naiura Vieira Pereira; Mariana Colombini Zaniboni; Mirian Nacagami Sotto; Alberto José da Silva Duarte; Maria Notomi Sato; Valeria Aoki
Journal:  Sci Rep       Date:  2018-04-27       Impact factor: 4.379

5.  Psychological Stress Deteriorates Skin Barrier Function by Activating 11β-Hydroxysteroid Dehydrogenase 1 and the HPA Axis.

Authors:  Sung Jay Choe; Donghye Kim; Eun Jung Kim; Joung-Sook Ahn; Eun-Jeong Choi; Eui Dong Son; Tae Ryong Lee; Eung Ho Choi
Journal:  Sci Rep       Date:  2018-04-20       Impact factor: 4.379

6.  The Tissue-Engineered Human Psoriatic Skin Substitute: A Valuable In Vitro Model to Identify Genes with Altered Expression in Lesional Psoriasis.

Authors:  Geneviève Rioux; Claudia Pouliot-Bérubé; Mélissa Simard; Manel Benhassine; Jacques Soucy; Sylvain L Guérin; Roxane Pouliot
Journal:  Int J Mol Sci       Date:  2018-09-26       Impact factor: 5.923

Review 7.  Glucocorticoids and Glucocorticoid-Induced-Leucine-Zipper (GILZ) in Psoriasis.

Authors:  Lisa M Sevilla; Paloma Pérez
Journal:  Front Immunol       Date:  2019-09-13       Impact factor: 7.561

Review 8.  Extra-adrenal glucocorticoid biosynthesis: implications for autoimmune and inflammatory disorders.

Authors:  Radomir M Slominski; Robert C Tuckey; Pulak R Manna; Anton M Jetten; Arnold Postlethwaite; Chander Raman; Andrzej T Slominski
Journal:  Genes Immun       Date:  2020-03-23       Impact factor: 2.676

9.  Melatonin inhibits attention-deficit/hyperactivity disorder caused by atopic dermatitis-induced psychological stress in an NC/Nga atopic-like mouse model.

Authors:  Gunhyuk Park; Young-Suk Jung; Moon-Ki Park; Chae Ha Yang; Yong-Ung Kim
Journal:  Sci Rep       Date:  2018-10-08       Impact factor: 4.379

Review 10.  Pathogenesis of psoriasis in the "omic" era. Part I. Epidemiology, clinical manifestation, immunological and neuroendocrine disturbances.

Authors:  Dominik Samotij; Bogusław Nedoszytko; Joanna Bartosińska; Aleksandra Batycka-Baran; Rafał Czajkowski; Iwona T Dobrucki; Lawrence W Dobrucki; Magdalena Górecka-Sokołowska; Anna Janaszak-Jasienicka; Dorota Krasowska; Leszek Kalinowski; Marta Macieja-Stawczyk; Roman J Nowicki; Agnieszka Owczarczyk-Saczonek; Agata Płoska; Dorota Purzycka-Bohdan; Adrianna Radulska; Edyta Reszka; Anna Siekierzycka; Andrzej Słomiński; Radomir Słomiński; Marta Sobalska-Kwapis; Dominik Strapagiel; Aneta Szczerkowska-Dobosz; Justyna Szczęch; Michał Żmijewski; Adam Reich
Journal:  Postepy Dermatol Alergol       Date:  2020-05-05       Impact factor: 1.837
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