Literature DB >> 28730389

Cardiovascular Effects of High-Molecular-Weight Compounds of Humic Nature.

M V Zykova1, M V Belousov2, T V Lasukova3,4, A S Gorbunov4, L A Logvinova2, A M Dygai5.   

Abstract

The active ingredient extracted from the peat humic substances was characterized by physicochemical parameters evaluated by UV- and IR-spectroscopy, titration, and elemental (C, H, N) analysis. The cardiovascular effects of this ingredient were examined on isolated Langendorff-perfused rat heart. It was found that the active substance in a concentration range of 0.01-0.1 mg/ml produced a vasodilating effect; in addition, it decreased the end-diastolic and left-ventricular developed pressures.

Entities:  

Keywords:  cardiovascular effects; heart; humic acids; peat

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Year:  2017        PMID： 28730389     DOI： 10.1007/s10517-017-3767-1

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  2 in total

1.  Quantitative Structure-Activity Relationship, Ontology-Based Model of the Antioxidant and Cell Protective Activity of Peat Humic Acids.

Authors:  Maria V Zykova; Konstantin S Brazovskii; Kristina A Bratishko; Evgeny E Buyko; Lyudmila A Logvinova; Sergey V Romanenko; Andrey I Konstantinov; Sergei V Krivoshchekov; Irina V Perminova; Mikhail V Belousov
Journal:  Polymers (Basel)       Date:  2022-08-12       Impact factor: 4.967

2.  Physicochemical Characterization and Antioxidant Activity of Humic Acids Isolated from Peat of Various Origins.

Authors:  Maria V Zykova; Igor A Schepetkin; Michael V Belousov; Sergey V Krivoshchekov; Lyudmila A Logvinova; Kristina A Bratishko; Mekhman S Yusubov; Sergey V Romanenko; Mark T Quinn
Journal:  Molecules       Date:  2018-03-24       Impact factor: 4.411
  2 in total

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