| Literature DB >> 28730382 |
Nedime Serakinci1,2, Pinar Tulay3, Rasime Kalkan3.
Abstract
Stem cells have the ability to perpetuate themselves through self-renewal and generate mature cells of a particular tissue through differentiation. Mesenchymal stem cells (MSCs) play an important role in tissue homeostasis - supporting tissue regeneration. MSCs are rare pluripotent cells supporting hematopoietic and mesenchymal cell lineages. MSCs have a great therapeutic potential in cancer therapy, as well as stem cell exosome and/or microvesicle-mediated tissue regeneration. In this review, the use of hMSCs in stem cell-mediated cancer therapy is discussed.Entities:
Keywords: Cancer development; Cancer therapy; Mesenchymal stem cells; Stem cell-mediated cancer therapy
Mesh:
Year: 2018 PMID: 28730382 DOI: 10.1007/5584_2017_64
Source DB: PubMed Journal: Adv Exp Med Biol ISSN: 0065-2598 Impact factor: 2.622