| Literature DB >> 28725448 |
Sarah Negash1, Charles Agyemang1, Tandi E Matsha2, Nasheeta Peer3,4, Rajiv T Erasmus5, Andre P Kengne3,4.
Abstract
BACKGROUND: Factors influencing the increasing prevalence of overweight/obesity among children and adolescents in sub-Saharan Africa remain unclear. We assessed the prevalence and determinants of overweight and obesity and effects on cardio-metabolic profile in school learners in the Western Cape, South Africa.Entities:
Keywords: Cardio-metabolic comorbidities; Cardiovascular diseases; Excess weight; Paediatrics
Year: 2017 PMID: 28725448 PMCID: PMC5514529 DOI: 10.1186/s40608-017-0165-1
Source DB: PubMed Journal: BMC Obes ISSN: 2052-9538
Socio-demographic and behavioural characteristics of participants presented by gender, population group and overall
| Characteristics | Overall | Gender | Population groups |
| |||||
|---|---|---|---|---|---|---|---|---|---|
| Male | Female |
| Coloured | Black | White |
| |||
| Number, | 1559 (100) | 619 (39.7) | 940 (60.3) | 877 (56.3) | 537 (34.5) | 145 (9.3) | |||
| Mean age, years (SD) | 12.9 ± 2.5 | 13.0 ± 2.6 | 12.8 ± 2.5 | 0.226 | 12.7 ± 2.6 | 12.9 ± 2.5 | 14.0 ± 2.0 | <0.0001 | 0.001 |
| Age group (years), | 0.165 | <0.0001 | <0.0001 | ||||||
| 7–9 | 185 (11.9) | 77 (12.4) | 108 (11.5) | 127 (14.5) | 51 (9.5) | 7 (4.8) | |||
| 10–12 | 483 (31.0) | 172 (27.8) | 311 (33.1) | 285 (32.5) | 183 (34.1) | 15 (10.3) | |||
| 13–15 | 626 (40.1) | 257 (41.5) | 369 (39.2) | 317 (36.1) | 209 (38.9) | 100 (69.0) | |||
| 16–18 | 265 (17.0) | 113 (18.3) | 152 (16.2) | 148 (16.9) | 94 (17.5) | 23 (15.9) | |||
| Location, | 0.043 | <0.0001 | <0.0001 | ||||||
| Rural | 142 (9.5) | 44 (7.4) | 98 (10.9) | 138 (16.7) | 4 (0.7) | - | |||
| Semi-urban | 448 (29.9) | 197 (33.1) | 251 (27.8) | 249 (30.1) | 199 (37.8) | - | |||
| Urban | 908 (60.6) | 355 (59.5) | 553 (61.3) | 441 (53.2) | 324 (61.5) | 143 (100) | |||
| Behavioural risk factors | |||||||||
| Physical inactivity**, | 423 (27.1) | 159 (25.7) | 264 (28.1) | 0.297 | 252 (28.7) | 119 (22.2) | 52 (35.9) | 0.001 | 0.003 |
| Sedentary behaviour***, | 1303 (83.6) | 507 (81.9) | 796 (84.7) | 0.004 | 709 (80.8) | 469 (87.3) | 125 (86.2) | 0.148 | 0.007 |
| Smoking | 122 (7.9) | 71 (11.5) | 51 (5.4) | <0.0001 | 85 (9.9) | 16 (3.0) | 21 (14.5) | <0.0001 | <0.0001 |
| Alcohol consumption | 223 (14.4) | 111 (17.9) | 112 (11.9) | 0.001 | 128 (14.7) | 51 (9.6) | 44 (30.3) | <0.0001 | <0.0001 |
| Dietary Diversity Score ≤ 4 | 667 (43.8) | 269 (44.6) | 398 (43.3) | 0.616 | 371 (43.7) | 273 (51.6) | 23 (16.0) | <0.0001 | <0.0001 |
21 missing (10 males; 11 females); (15 Coloured; 6 Black learners)
*P-value for the interaction of population group and gender; **participating in sport and/or walking on ≤2 days/week; ***television watching 3–5 days/week
Prevalence of adiposity and cardio-metabolic comorbidities by gender, population group and overall
| Variables, | Overall | Gender | Population groups | P for population group* gender* | |||||
|---|---|---|---|---|---|---|---|---|---|
| Boys | Girls |
| Coloured | Black | White |
| |||
|
| 1559 (100) | 619 (39.7) | 940 (60.3) | 877 (56.3) | 537 (34.5) | 145 (9.3) | |||
| Body Mass Index categories | <0.0001 | <0.0001 | <0.0001 | ||||||
| Normal weight | 1202 (77.1) | 533 (86.1) | 669 (71.2) | 699 (79.7) | 398 (74.1) | 105 (72.4) | |||
| Overweight | 243 (15.6) | 58 (9.4) | 185 (19.7) | 112 (12.8) | 101 (18.8) | 30 (20.7) | |||
| Obesity | 114 (7.3) | 28 (4.5) | 86 (9.1) | 66 (7.5) | 38 (7.1) | 10 (6.9) | |||
| Hypertension | 38 (2.6) | 17 (2.9) | 21 (2.4) | 0.748 | 17 (2.0) | 18 (3.6) | 3 (2.2) | 0.038 | 0.072 |
| Dyslipidaemia | |||||||||
| Triglycerides >1.5 mmol/L | 78 (5.0) | 26 (4.2) | 52 (5.5) | 0.238 | 42 (4.8) | 29 (5.4) | 7 (4.8) | 0.873 | 0.040 |
| Total cholesterol >5 mmol/L | 102 (6.5) | 28 (4.5) | 74 (7.9) | 0.009 | 61 (7.0) | 27 (5.0) | 14 (9.7) | 0.102 | 0.034 |
| HDL-C < 1.2 mmol/L | 1047 (67.2) | 459 (74.2) | 588 (62.6) | <0.0001 | 593 (67.6) | 339 (63.1) | 115 (79.3) | 0.001 | <0.0001 |
*P-value for the interaction of population group and gender; Overweight and obesity: Gender- and age-specific BMI cut-off points corresponding to 25 and 30 kg/m2, respectively, at the age of 18 years (17); Hypertension: systolic and/or diastolic blood pressure equal to the 95th percentile for gender, age and height (16)
Stepwise multivariable logistic regression model for the associations of socio-demographic and behavioural factors with overweight/obesity
| Variables | Basic model | Expanded model | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI |
| OR | 95% CI |
| |
| Gender | ||||||
| Boys | 1 | 1 | ||||
| Girls | 2.53 | 1.94–3.32 | <0.0001 | 2.51 | 1.92–3.29 | <0.0001 |
| Age groups, years | 0.325 | 0.325 | ||||
| 7–9 | 1 | 1 | ||||
| 10–12 | 1.16 | 0.75–1.80 | 0.509 | 1.21 | 0.78–1.87 | 0.404 |
| 13–15 | 1.36 | 0.89–2.07 | 0.161 | 1.39 | 0.91–2.12 | 0.132 |
| 16–18 | 1.40 | 0.87–2.24 | 0.167 | 1.45 | 0.90–2.33 | 0.130 |
| Population groups | 0.019 | 0.019 | ||||
| Coloured | 1 | 1 | ||||
| Black | 1.33 | 1.02–1.72 | 0.032 | 1.35 | 1.04–1.75 | 0.024 |
| White | 1.48 | 0.98–2.25 | 0.063 | 1.45 | 0.96–2.21 | 0.080 |
| Region | 0.540 | |||||
| Rural | 1 | |||||
| Semi-urban | 1.36 | 0.81–2.25 | 0.242 | - | - | - |
| Urban | 1.50 | 0.89–2.53 | 0.130 | - | - | - |
| Eating breakfast | ||||||
| No | 1 | |||||
| Yes | 0.83 | 0.63–1.08 | 0.165 | - | - | - |
| Physical inactivity | ||||||
| No | 1 | 1 | ||||
| Yes | 1.32 | 1.01–1.72 | 0.047 | 1.32 | 1.01–1.72 | 0.047 |
| Sedentary behaviour | ||||||
| No | 1 | |||||
| Yes | 1.21 | 0.86–1.70 | 0.284 | - | - | - |
| Smoking | ||||||
| No | 1 | |||||
| Yes | 0.80 | 0.48–1.33 | 0.396 | - | - | - |
| Alcohol | ||||||
| No | 1 | |||||
| Yes | 0.97 | 0.67–1.41 | 0.873 | - | - | - |
Gender: adjusted for age and population groups; Age group: adjusted for gender and population group; Population group: adjusted for gender and age group; Physical inactivity: adjusted for gender, age and population groups; Physical inactivity: Sport and/or walking ≤2 days/week
Odds ratios (OR) and 95% confidence intervals (CI) for the associations of cardio-metabolic comorbidities with overweight/obesity
| Outcomes | Overalla | Population groupsb | ||||||
|---|---|---|---|---|---|---|---|---|
| Coloured | Black | White | ||||||
| OR (95% CI) |
| OR (95% CI) |
| OR (95% CI) |
| OR (95% CI) |
| |
| Hypertension | ||||||||
| No | 1 | 1 | 1 | 1 | ||||
| Yes | 3.02 (1.52–6.00) | 0.002 | 3.27 (1.18–9.08) | 0.023 | 3.62 (1.31–10.04) | 0.013 | 1.63 (0.14–19.52) | 0.702 |
| Triglycerides > 1.5 mmol/L | ||||||||
| No | 1 | 1 | 1 | 1 | ||||
| Yes | 1.83 (1.12–2.99) | 0.016 | 1.94 (0.99–3.78) | 0.053 | 1.22 (0.52–2.88) | 0.642 | 4.0 (0.79–20.21) | 0.095 |
| Total cholesterol > 5 mmol/L | ||||||||
| No | 1 | 1 | 1 | 1 | ||||
| Yes | 1.04 (0.65–1.68) | 0.869 | 0.61 (0.29–1.28) | 0.189 | 1.86 (0.82–4.19) | 0.137 | 1.40 (0.43–4.56) | 0.574 |
| HDL-C < 1.2 mmol/L | ||||||||
| No | 1 | 1 | 1 | 1 | ||||
| Yes | 2.53 (1.89–3.40) | <0.0001 | 3.65 (2.33–5.72) | <0.0001 | 1.56 (1.01–2.40) | 0.046 | 5.04 (1.35–18.80) | 0.016 |
aAdjusted for age, gender and population group; bAdjusted for age and gender; Hypertension: systolic and/or diastolic blood pressure equal to the 95th percentile for gender, age and height