Literature DB >> 2872433

Parkinsonism, tardive dyskinesia, akathisia, and depression induced by flunarizine.

C Chouza, A Scaramelli, J L Caamaño, O De Medina, R Aljanati, S Romero.   

Abstract

12 subjects, 8 women and 4 men, presented with extrapyramidal motor signs and psychic depression after treatment with flunarizine for between 3 weeks and 15 months. One woman presented with severe symptoms and 20 months after stopping flunarizine she still had dyskinesia and akathisia. The other patients showed partial or complete improvement after withdrawal of the drug.

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Year:  1986        PMID: 2872433     DOI: 10.1016/s0140-6736(86)91223-7

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  31 in total

1.  Some central pharmacological effects of the calcium channel antagonist flunarizine.

Authors:  A Czyrak; E Mogilnicka; J Maj
Journal:  J Neural Transm Gen Sect       Date:  1991

Review 2.  Do calcium antagonists have a place in the treatment of mood disorders?

Authors:  C Höschl
Journal:  Drugs       Date:  1991-11       Impact factor: 9.546

Review 3.  Essential tremor.

Authors:  Joaquim Jos Ferreira; Cristina Sampaio
Journal:  BMJ Clin Evid       Date:  2007-05-01

4.  A postmarketing study of flunarizine in migraine and vertigo.

Authors:  G H de Bock; J Eelhart; H W van Marwijk; T P Tromp; M P Springer
Journal:  Pharm World Sci       Date:  1997-12

5.  Drug-induced parkinsonism: prevalence, clinical features and follow-up study in three Sicilian communities.

Authors:  L Morgante; A E Di Rosa; G Savettieri; A Reggio; F Patti; G Salemi; G Di Lorenzo; A Epifanio; R Di Perri
Journal:  J Neurol       Date:  1996-03       Impact factor: 4.849

6.  Tardive dyskinesia risk with first- and second-generation antipsychotics in comparative randomized controlled trials: a meta-analysis.

Authors:  Maren Carbon; John M Kane; Stefan Leucht; Christoph U Correll
Journal:  World Psychiatry       Date:  2018-10       Impact factor: 49.548

7.  Risk of parkinsonism induced by flunarizine or cinnarizine: a population-based study.

Authors:  Hsiu-Li Lin; Hsiu-Chen Lin; Yuan-Fu Tseng; Shih-Chang Chen; Chien-Yeh Hsu
Journal:  Eur J Clin Pharmacol       Date:  2016-12-16       Impact factor: 2.953

8.  Depression associated with diltiazem.

Authors:  C Biriell; J McEwen; E Sanz
Journal:  BMJ       Date:  1989-09-23

9.  Aggravation of Parkinson's disease by cinnarizine.

Authors:  J F Martí Massó; J A Obeso; N Carrera; J M Martínez-Lage
Journal:  J Neurol Neurosurg Psychiatry       Date:  1987-06       Impact factor: 10.154

10.  Cyclandelate versus flunarizine. A double-blind study in a selected group of patients with dementia.

Authors:  M G Albizzati; S Bassi; E Calloni; M Sbacchi; R Piolti; L Frattola
Journal:  Drugs       Date:  1987       Impact factor: 9.546

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