Literature DB >> 28718436

tRNA Modification: Is Cancer Having a Wobble?

Francesca Rapino1, Sylvain Delaunay1, Zhaoli Zhou1, Alain Chariot2, Pierre Close3.   

Abstract

Translational control of protein synthesis supports tumor development and progression to metastasis. Wobble tRNA modifications are required during translation elongation and sustain proteome homeostasis. Recent work has highlighted the surprising upregulation of the wobble uridine 34 (U34) tRNA cascade in cancer, which underlies the specific requirement for this pathway in tumor development.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  cancer; mRNA translation; proteome regulation; wobble tRNA modification

Mesh：

Substances：

Year:  2017        PMID： 28718436     DOI： 10.1016/j.trecan.2017.02.004

Source DB:  PubMed          Journal:  Trends Cancer        ISSN： 2405-8025


  19 in total

1.  Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression.

Authors:  Julie Lorent; Eric P Kusnadi; Vincent van Hoef; Richard J Rebello; Matthew Leibovitch; Johannes Ristau; Shan Chen; Mitchell G Lawrence; Krzysztof J Szkop; Baila Samreen; Preetika Balanathan; Francesca Rapino; Pierre Close; Patricia Bukczynska; Karin Scharmann; Itsuhiro Takizawa; Gail P Risbridger; Luke A Selth; Sebastian A Leidel; Qishan Lin; Ivan Topisirovic; Ola Larsson; Luc Furic
Journal:  EMBO J       Date:  2019-09-26       Impact factor: 11.598

Review 2.  Role of RNA modifications in cancer.

Authors:  Isaia Barbieri; Tony Kouzarides
Journal:  Nat Rev Cancer       Date:  2020-04-16       Impact factor: 60.716

3.  Dynamic changes in tRNA modifications and abundance during T cell activation.

Authors:  Roni Rak; Michal Polonsky; Inbal Eizenberg-Magar; Yufeng Mo; Yuriko Sakaguchi; Orel Mizrahi; Aharon Nachshon; Shlomit Reich-Zeliger; Noam Stern-Ginossar; Orna Dahan; Tsutomu Suzuki; Nir Friedman; Yitzhak Pilpel
Journal:  Proc Natl Acad Sci U S A       Date:  2021-10-19       Impact factor: 11.205

Review 4.  The Key Role of RNA Modification in Breast Cancer.

Authors:  Yang Liu; Tong Zhu; Yi Jiang; Jiawen Bu; Xudong Zhu; Xi Gu
Journal:  Front Cell Dev Biol       Date:  2022-06-01

Review 5.  RNA modifications regulating cell fate in cancer.

Authors:  Sylvain Delaunay; Michaela Frye
Journal:  Nat Cell Biol       Date:  2019-05-02       Impact factor: 28.824

Review 6.  The occurrence order and cross-talk of different tRNA modifications.

Authors:  Jing Li; Wen-Yu Zhu; Wen-Qing Yang; Cai-Tao Li; Ru-Juan Liu
Journal:  Sci China Life Sci       Date:  2021-04-19       Impact factor: 6.038

7.  Wobble uridine tRNA modification: a new vulnerability of refractory melanoma.

Authors:  Francesca Rapino; Pierre Close
Journal:  Mol Cell Oncol       Date:  2018-09-25

8.  miRNA deregulation targets specific pathways in leiomyosarcoma development: an in silico analysis.

Authors:  Clara Benna; Senthilkumar Rajendran; Marco Rastrelli; Simone Mocellin
Journal:  J Transl Med       Date:  2019-05-14       Impact factor: 5.531

Review 9.  From Translation to Protein Degradation as Mechanisms for Regulating Biological Functions: A Review on the SLRP Family in Skeletal Tissues.

Authors:  Jérémie Zappia; Marc Joiret; Christelle Sanchez; Cécile Lambert; Liesbet Geris; Marc Muller; Yves Henrotin
Journal:  Biomolecules       Date:  2020-01-03

10.  Genomic Landscape of Intramedullary Spinal Cord Gliomas.

Authors:  Ming Zhang; Rajiv R Iyer; Tej D Azad; Qing Wang; Tomas Garzon-Muvdi; Joanna Wang; Ann Liu; Peter Burger; Charles Eberhart; Fausto J Rodriguez; Daniel M Sciubba; Jean-Paul Wolinsky; Ziya Gokaslan; Mari L Groves; George I Jallo; Chetan Bettegowda
Journal:  Sci Rep       Date:  2019-12-10       Impact factor: 4.379
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