Literature DB >> 28718297

Determination of Aerobic Capacity via Cycle Ergometer Exercise Testing in Alzheimer's Disease.

Ulf G Bronas1, Dereck Salisbury2, Kaitlin Kelly2, Arthur Leon3, Lisa Chow4, Fang Yu2.   

Abstract

BACKGROUND: Older adults with Alzheimer's disease (AD) may be unable to perform treadmill testing due to balance issues. We investigated whether older adults with AD could successfully complete a peak cycle ergometer test.
METHODS: Peak oxygen consumption (peak [Formula: see text]) assessed via a cycle ergometer test in 44 participants with AD (age 78.4 ± 6.8). Physical function was assessed via the incremental shuttle walk, 6-minute walk, and the Short Physical Performance Battery (SPPB).
RESULTS: All participants completed the cycle ergometer test successfully. Peak [Formula: see text] was correlated with SPPB ( r = .35, P = .023), shuttle walk ( r = .35, P = .024), 6-minute walk ( r = .31, P = .05), and inversely with age ( r = -.4, P = .009). There was no correlation between peak [Formula: see text] and cognition.
CONCLUSION: Older adults with AD are able to safely complete a peak cycle ergometer exercise testing protocol. We provide an individualized cycle ergometer test for determining aerobic capacity in older adults with AD who may be unable to perform treadmill testing due to balance or gait issues.

Entities:  

Keywords:  Alzheimer’s disease; aging; cardiorespiratory fitness; cycle ergometer; dementia; physical function

Mesh:

Year:  2017        PMID: 28718297      PMCID: PMC7783779          DOI: 10.1177/1533317517720065

Source DB:  PubMed          Journal:  Am J Alzheimers Dis Other Demen        ISSN: 1533-3175            Impact factor:   2.035


  37 in total

1.  Lower extremity function and subsequent disability: consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery.

Authors:  J M Guralnik; L Ferrucci; C F Pieper; S G Leveille; K S Markides; G V Ostir; S Studenski; L F Berkman; R B Wallace
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2000-04       Impact factor: 6.053

2.  Comparison of motor strategies in sit-to-stand and back-to-sit motions between healthy and Alzheimer's disease elderly subjects.

Authors:  P Manckoundia; F Mourey; P Pfitzenmeyer; C Papaxanthis
Journal:  Neuroscience       Date:  2005-11-14       Impact factor: 3.590

3.  Maintaining physical fitness and function in Alzheimer's disease: a pilot study.

Authors:  Fang Yu; Kay Savik; Jean F Wyman; Ulf G Bronas
Journal:  Am J Alzheimers Dis Other Demen       Date:  2011-07-12       Impact factor: 2.035

4.  Maximum and submaximum exercise tests in men and women in the seventh, eighth, and ninth decades of life.

Authors:  K H Sidney; R J Shephard
Journal:  J Appl Physiol Respir Environ Exerc Physiol       Date:  1977-08

Review 5.  A qualitative systematic overview of the measurement properties of functional walk tests used in the cardiorespiratory domain.

Authors:  S Solway; D Brooks; Y Lacasse; S Thomas
Journal:  Chest       Date:  2001-01       Impact factor: 9.410

6.  The trajectory of gait speed preceding mild cognitive impairment.

Authors:  Teresa Buracchio; Hiroko H Dodge; Diane Howieson; Dara Wasserman; Jeffrey Kaye
Journal:  Arch Neurol       Date:  2010-08

Review 7.  Aerobic exercise effects on cognitive and neural plasticity in older adults.

Authors:  K I Erickson; A F Kramer
Journal:  Br J Sports Med       Date:  2008-10-16       Impact factor: 13.800

8.  Alzheimer disease alters the relationship of cardiorespiratory fitness with brain activity during the stroop task.

Authors:  Eric D Vidoni; Matthew R Gayed; Robyn A Honea; Cary R Savage; Derek Hobbs; Jeffrey M Burns
Journal:  Phys Ther       Date:  2013-04-04

9.  Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability.

Authors:  J M Guralnik; L Ferrucci; E M Simonsick; M E Salive; R B Wallace
Journal:  N Engl J Med       Date:  1995-03-02       Impact factor: 91.245

Review 10.  A review of the effects of physical activity and exercise on cognitive and brain functions in older adults.

Authors:  Louis Bherer; Kirk I Erickson; Teresa Liu-Ambrose
Journal:  J Aging Res       Date:  2013-09-11
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  4 in total

1.  Exercise Training and Cognitive Function in Kidney Disease: Protocol for a Pilot Randomized Controlled Trial.

Authors:  Ulf G Bronas; Mary Hannan; James P Lash; Olu Ajilore; Xiaohong Joe Zhou; Melissa Lamar
Journal:  Nurs Res       Date:  2022 Jan-Feb 01       Impact factor: 2.381

2.  Recommended motor assessments based on psychometric properties in individuals with dementia: a systematic review.

Authors:  Sandra Trautwein; Philipp Maurus; Bettina Barisch-Fritz; Anela Hadzic; Alexander Woll
Journal:  Eur Rev Aging Phys Act       Date:  2019-11-03       Impact factor: 3.878

3.  Physical fitness in institutionalized older adults with dementia: association with cognition, functional capacity and quality of life.

Authors:  A Sampaio; I Marques-Aleixo; A Seabra; J Mota; E Marques; J Carvalho
Journal:  Aging Clin Exp Res       Date:  2020-01-11       Impact factor: 3.636

4.  Change in Fitness and the Relation to Change in Cognition and Neuropsychiatric Symptoms After Aerobic Exercise in Patients with Mild Alzheimer's Disease.

Authors:  Nanna A Sobol; Christian Have Dall; Peter Høgh; Kristine Hoffmann; Kristian Steen Frederiksen; Asmus Vogel; Volkert Siersma; Gunhild Waldemar; Steen G Hasselbalch; Nina Beyer
Journal:  J Alzheimers Dis       Date:  2018       Impact factor: 4.472

  4 in total

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