Literature DB >> 28713683

Do we really care about incidental lung nodules?-Review of atypical lung carcinoid and a proposal for systematic patient follow up.

Henal Motiwala1, Itisha Bansal2, Pradeep Goyal3, Olena Dorokhova4, Yogesh Kumar5, Thomas D Olsavsky6, Albert DiMeo7, Nishant Gupta3.   

Abstract

Atypical lung carcinoids are intermediate-grade neuroendocrine tumors (NETs) with malignant potential. They are often detected incidentally on imaging done for non-related causes, as the patients are frequently asymptomatic. Histopathology is required to confirm the diagnosis with immunohistochemistry (IHC). Due to their indolent nature, these are often diagnosed only in the advanced stages. Treatment options include chemoradiation for widespread disease versus surgery for local or minimally invasive disease. This article describes a nonsmoker female with enlarging solitary pulmonary nodule who was initially lost to follow up, subsequently operated and with final pathology revealing atypical lung carcinoid. This case stress on the schematic follow up of these incidentally detected pulmonary nodules. Inspired from the mandatory lay mammography report letters recommended by ACR, this article proposes sending lay letters to patients for pulmonary nodule follow up, directly from the Radiology Department to reinforce the importance of timely follow up, which will complement the information provided to the patient from their primary care physician or pulmonologist's office.

Entities:  

Keywords:  Solitary pulmonary nodule; atypical carcinoids (ACs); lung carcinoids; neuroendocrine tumors (NETs)

Year:  2017        PMID: 28713683      PMCID: PMC5504111          DOI: 10.21037/tlcr.2017.05.05

Source DB:  PubMed          Journal:  Transl Lung Cancer Res        ISSN: 2218-6751


  13 in total

1.  Follow-up of Incidental Pulmonary Nodules and the Radiology Report.

Authors:  Denitza P Blagev; James F Lloyd; Karen Conner; Justin Dickerson; Daniel Adams; Scott M Stevens; Scott C Woller; R Scott Evans; C Gregory Elliott
Journal:  J Am Coll Radiol       Date:  2016-02       Impact factor: 5.532

Review 2.  Neuroendocrine tumors of the bronchopulmonary system (typical and atypical carcinoid tumors): current strategies in diagnosis and treatment. Conclusions of an expert meeting February 2011 in Weimar, Germany.

Authors:  Dieter Hörsch; Kurt W Schmid; Martin Anlauf; Kaid Darwiche; Tim Denecke; Richard P Baum; Christine Spitzweg; Christian Grohé; Norbert Presselt; Christian Stremmel; David F Heigener; Monika Serke; Thomas Kegel; Marianne Pavel; Cornelius F Waller; Karl-Matthias Deppermann; Rudolf Arnold; Rudolf M Huber; Matthias M Weber; Hans Hoffmann
Journal:  Oncol Res Treat       Date:  2014-04-14       Impact factor: 2.825

Review 3.  Clinical presentation and evaluation of neuroendocrine tumors of the lung.

Authors:  Frank C Detterbeck
Journal:  Thorac Surg Clin       Date:  2014-08       Impact factor: 1.750

Review 4.  Current understanding and approach to well differentiated lung neuroendocrine tumors: an update on classification and management.

Authors:  Talal Hilal
Journal:  Ther Adv Med Oncol       Date:  2016-11-17       Impact factor: 8.168

5.  Ways to improve radiologists' adherence to Fleischner Society guidelines for management of pulmonary nodules.

Authors:  Ronald L Eisenberg
Journal:  J Am Coll Radiol       Date:  2013-03-29       Impact factor: 5.532

6.  Carcinoid lung tumors--incidence, treatment and outcomes: a population-based study.

Authors:  Anne Naalsund; Hans Rostad; Erik Heyerdahl Strøm; May Brit Lund; Trond-Eirik Strand
Journal:  Eur J Cardiothorac Surg       Date:  2011-04       Impact factor: 4.191

Review 7.  Multidisciplinary management of advanced lung neuroendocrine tumors.

Authors:  Pier Luigi Filosso; Piero Ferolla; Francesco Guerrera; Enrico Ruffini; William D Travis; Giulio Rossi; Paolo Olivo Lausi; Alberto Oliaro
Journal:  J Thorac Dis       Date:  2015-04       Impact factor: 2.895

Review 8.  Bronchopulmonary neuroendocrine tumors.

Authors:  Bjorn I Gustafsson; Mark Kidd; Anthony Chan; Max V Malfertheiner; Irvin M Modlin
Journal:  Cancer       Date:  2008-07-01       Impact factor: 6.860

Review 9.  Challenges in the Diagnosis and Management of Well-Differentiated Neuroendocrine Tumors of the Lung (Typical and Atypical Carcinoid): Current Status and Future Considerations.

Authors:  Edward M Wolin
Journal:  Oncologist       Date:  2015-08-25

10.  Telotristat etiprate, a novel serotonin synthesis inhibitor, in patients with carcinoid syndrome and diarrhea not adequately controlled by octreotide.

Authors:  Matthew H Kulke; Thomas O'Dorisio; Alexandria Phan; Emily Bergsland; Linda Law; Phillip Banks; Joel Freiman; Kenny Frazier; Jessica Jackson; James C Yao; Larry Kvols; Pablo Lapuerta; Brian Zambrowicz; Douglas Fleming; Arthur Sands
Journal:  Endocr Relat Cancer       Date:  2014-07-10       Impact factor: 5.678

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  4 in total

1.  A case of pulmonary arteriovenous malformation: role of interventional radiology in diagnosis and treatment.

Authors:  Pranav Sharma; Puneet Kochar; Salil Sharma; Nishant Gupta; Shuo Li; Kusum Hooda; Yogesh Kumar
Journal:  Ann Transl Med       Date:  2017-09

2.  A Rare Case of an Azygos Lobe in the Right Lung of a 40-year-old Male.

Authors:  Georgi Kotov; Iva N Dimitrova; Alexandar Iliev; Violeta Groudeva
Journal:  Cureus       Date:  2018-06-11

3.  Computed Tomographic Studies of Noncalcified Nodules Related to Neuroendocrine Lung Tumor Using 68Gallium-Tagged Somatostatin Variant for Improvement in Diagnosis: A Non-Experimental, Non-Randomized, Cross-Sectional Study.

Authors:  Ketian Li; Mingge Shen; Hang Geng; Linyi Zheng; Yujie Cao
Journal:  Med Sci Monit       Date:  2018-06-30

4.  Retrospective Analysis of Clinicopathological Features and Prognosis of Gynecological Small-Cell Carcinoma.

Authors:  Li Pang; Hui Yang; Yuer Ning; Chunyu Zheng
Journal:  Cancer Manag Res       Date:  2021-06-08       Impact factor: 3.989

  4 in total

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