Md Jalaluddin1, U B Rajasekaran2, Sam Paul3, R S Dhanya4, C B Sudeep5, V J Adarsh6. 1. Department of Periodontics and Oral Implantology, Kalinga Institute of Dental Sciences, Kalinga Institute of Industrial Technology University, Bhubaneswar, Odisha, India, e-mail: drjalal79@yahoo.co.in. 2. Department of Orthodontics and Dentofacial Orthopedics, Sibar Institute of Dental Sciences, Guntur, Andhra Pradesh, India. 3. Department of Orthodontics and Dentofacial Orthopedics Educare Institute of Dental Sciences, Malappuram, Kerala, India. 4. Department of Public Health Dentistry, PSM College of Dental Science & Research, Thrissur, Kerala, India. 5. Department of Public Health Dentistry, Sree Anjaneya Institute of Dental Sciences, Kozhikode, Kerala, India. 6. Department of Conservative Dentistry and Endodontics, Mahe Institute of Dental Sciences, Mahe, Puducherry, India.
Abstract
AIM: The present study aimed at evaluating the impact of neem-containing mouthwash on plaque and gingivitis. MATERIALS AND METHODS: This randomized, double-blinded, crossover clinical trial included 40 participants aged 18 to 35 years with washout period of 1 week between the crossover phases. A total of 20 participants, each randomly allocated into groups I and II, wherein in the first phase, group I was provided with 0.2% chlorhexidine gluconate and group II with 2% neem mouthwash. After the scores were recorded, 1-week time period was given to the participants to carry over the effects of the mouthwashes and then the second phase of the test was performed. The participants were instructed to use the other mouthwash through the second test phase. RESULTS: There was a slight reduction of plaque level in the first phase as well as in the second phase. When comparison was made between the groups, no statistically significant difference was seen. Both the groups showed reduction in the gingival index (GI) scores in the first phase, and there was a statistically significant difference in both groups at baseline and after intervention (0.005 and 0.01 respectively). In the second phase, GI scores were reduced in both groups, but there was a statistically significant difference between the groups only at baseline scores (0.01). CONCLUSION: In the present study, it has been concluded that neem mouthwash can be used as an alternative to chlorhexidine mouthwash based on the reduced scores in both the groups. CLINICAL SIGNIFICANCE: Using neem mouthwash in maintaining oral hygiene might have a better impact in prevention as well as pervasiveness of oral diseases as it is cost-effective and easily available.
RCT Entities:
AIM: The present study aimed at evaluating the impact of neem-containing mouthwash on plaque and gingivitis. MATERIALS AND METHODS: This randomized, double-blinded, crossover clinical trial included 40 participants aged 18 to 35 years with washout period of 1 week between the crossover phases. A total of 20 participants, each randomly allocated into groups I and II, wherein in the first phase, group I was provided with 0.2% chlorhexidine gluconate and group II with 2% neem mouthwash. After the scores were recorded, 1-week time period was given to the participants to carry over the effects of the mouthwashes and then the second phase of the test was performed. The participants were instructed to use the other mouthwash through the second test phase. RESULTS: There was a slight reduction of plaque level in the first phase as well as in the second phase. When comparison was made between the groups, no statistically significant difference was seen. Both the groups showed reduction in the gingival index (GI) scores in the first phase, and there was a statistically significant difference in both groups at baseline and after intervention (0.005 and 0.01 respectively). In the second phase, GI scores were reduced in both groups, but there was a statistically significant difference between the groups only at baseline scores (0.01). CONCLUSION: In the present study, it has been concluded that neem mouthwash can be used as an alternative to chlorhexidine mouthwash based on the reduced scores in both the groups. CLINICAL SIGNIFICANCE: Using neem mouthwash in maintaining oral hygiene might have a better impact in prevention as well as pervasiveness of oral diseases as it is cost-effective and easily available.
Entities:
Keywords:
Chlorhexidine gluconate; Gingival index; Gingivitis; Neem mouthwash Plaque index.