Literature DB >> 28713068

Implementation of Good Laboratory Practices (GLP) in basic scientific research: Translating the concept beyond regulatory compliance.

G B Jena1, Sapana Chavan2.   

Abstract

The principles of Good Laboratory Practices (GLPs) are mainly intended for the laboratories performing studies for regulatory compliances. However, today GLP can be applied to broad disciplines of science to cater to the needs of the experimental objectives, generation of quality data and assay reproducibility. Considering its significance, it can now be applied in academics; industries as well as government set ups throughout the world. GLP is the best way to promote the reliability, reproducibility of the test data and hence facilitates the international acceptability. Now it is high time to translate and implement the concept of GLP beyond regulatory studies. Thus, it can pave the way for better understanding of scientific problems and help to maintain a good human and environmental health. Through this review, we have made an attempt to explore the uses of GLP principles in different fields of science and its acceptability as well as looking for its future perspectives.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Good laboratory practices; Regulatory toxicology; Reliability; Reproducibility; Research in basic science

Mesh:

Year:  2017        PMID: 28713068     DOI: 10.1016/j.yrtph.2017.07.010

Source DB:  PubMed          Journal:  Regul Toxicol Pharmacol        ISSN: 0273-2300            Impact factor:   3.271


  3 in total

1.  The lab management practices of "Research Exemplars" that foster research rigor and regulatory compliance: A qualitative study of successful principal investigators.

Authors:  Alison L Antes; Ashley Kuykendall; James M DuBois
Journal:  PLoS One       Date:  2019-04-24       Impact factor: 3.240

2.  Impact of Organization for Economic Co-Operation and Development (OECD) principles of Good Laboratory practices (GLP) in India.

Authors:  Ekta Kapoor; Neeraj Sharma; Rupa Joshi; Bikash Medhi
Journal:  Indian J Pharmacol       Date:  2021 Sep-Oct       Impact factor: 1.200

3.  Visually guided preprocessing of bioanalytical laboratory data using an interactive R notebook (pguIMP).

Authors:  Sebastian Malkusch; Lisa Hahnefeld; Robert Gurke; Jörn Lötsch
Journal:  CPT Pharmacometrics Syst Pharmacol       Date:  2021-10-01
  3 in total

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