Literature DB >> 28712691

Biliary bile acids in hepatobiliary injury - What is the link?

Peter Fickert1, Martin Wagner2.   

Abstract

The main trigger for liver injury in acquired cholestatic liver disease remains unclear. However, the accumulation of bile acids (BAs) undoubtedly plays a role. Recent progress in deciphering the pathomechanisms of inborn cholestatic liver diseases, decoding mechanisms of BA-induced cell death, and generating modern BA-derived drugs has improved the understanding of the regulation of BA synthesis and transport. Now is the appropriate time to reassess current knowledge about the specific role of BAs in hepatobiliary injury.
Copyright © 2017 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Bile canaliculus; Bile ducts; Bile secretion; Cholangiopathies; Cholangitis; Primary biliary cholangitis; Primary sclerosing cholangitis

Mesh：

Substances：

Year:  2017        PMID： 28712691     DOI： 10.1016/j.jhep.2017.04.026

Source DB:  PubMed          Journal:  J Hepatol        ISSN： 0168-8278            Impact factor:   25.083


  52 in total

Review 1.  Microbial Profiles of Cirrhosis in the Human Small Intestine.

Authors:  Tien S Dong; Jonathan P Jacobs; Shehnaz K Hussain
Journal:  Curr Gastroenterol Rep       Date:  2019-08-23

2.  Regulation of bile acid metabolism in mouse models with hydrophobic bile acid composition.

Authors:  Akira Honda; Teruo Miyazaki; Junichi Iwamoto; Takeshi Hirayama; Yukio Morishita; Tadakuni Monma; Hajime Ueda; Seiya Mizuno; Fumihiro Sugiyama; Satoru Takahashi; Tadashi Ikegami
Journal:  J Lipid Res       Date:  2019-10-23       Impact factor: 5.922

Review 3.  Animal models to study bile acid metabolism.

Authors:  Jianing Li; Paul A Dawson
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2018-05-18       Impact factor: 5.187

4.  Gut microbiome in liver pathophysiology and cholestatic liver disease.

Authors:  Shengmin Yan; Xiao-Ming Yin
Journal:  Liver Res       Date:  2021-08-08

Review 5.  Blood-Bile Barrier: Morphology, Regulation, and Pathophysiology.

Authors:  Tirthadipa Pradhan-Sundd; Satdarshan Pal Monga
Journal:  Gene Expr       Date:  2019-01-15

6.  Serum levels of a cell death biomarker predict the development of cirrhosis-related conditions in primary biliary cholangitis.

Authors:  Manabu Hayashi; Kazumichi Abe; Masashi Fujita; Ken Okai; Atsushi Takahashi; Yoshihiro Nozawa; Hiromasa Ohira
Journal:  Med Mol Morphol       Date:  2018-01-29       Impact factor: 2.309

7.  Repopulation of intrahepatic bile ducts in engineered rat liver grafts.

Authors:  Yibin Chen; Julie Devalliere; Beyza Bulutoglu; Martin L Yarmush; Basak E Uygun
Journal:  Technology (Singap World Sci)       Date:  2019-06-28

8.  Development of liver microtissues with functional biliary ductular network.

Authors:  Ehab O A Hafiz; Beyza Bulutoglu; Soheir S Mansy; Yibin Chen; Hoda Abu-Taleb; Somia A M Soliman; Ali A F El-Hindawi; Martin L Yarmush; Basak E Uygun
Journal:  Biotechnol Bioeng       Date:  2020-09-14       Impact factor: 4.530

Review 9.  A Current Understanding of Bile Acids in Chronic Liver Disease.

Authors:  Naba Farooqui; Anshuman Elhence
Journal:  J Clin Exp Hepatol       Date:  2021-08-23

10.  Bile Acid Profiles in Primary Sclerosing Cholangitis and Their Ability to Predict Hepatic Decompensation.

Authors:  Omar Y Mousa; Brian D Juran; Bryan M McCauley; Mette N Vesterhus; Trine Folseraas; Coleman T Turgeon; Ahmad H Ali; Erik M Schlicht; Elizabeth J Atkinson; Chang Hu; Denise Harnois; Elizabeth J Carey; Andrea A Gossard; Devin Oglesbee; John E Eaton; Nicholas F LaRusso; Gregory J Gores; Tom H Karlsen; Konstantinos N Lazaridis
Journal:  Hepatology       Date:  2021-06-15       Impact factor: 17.425
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