Na Zhang1,2, Lei Cheng2, Min Chen2, Jian Chen2, Yue Yang2, Ming Xie2, Cai Li2, Xiao-Ling Chen2, Liang Zhou2, Hai-Tao Wu2. 1. a Department of Otolaryngology Head and Neck Surgery , First Central Hospital, Otorhinolaryngology Institute of Tianjin , Tianjin , China. 2. b Department of Otolaryngology-Head and Neck Surgery , EENT Hospital, Fudan University , Shanghai , China.
Abstract
BACKGROUND: To explore the relationship between the morphological characteristics and pathological diagnosis of vocal cords leukoplakia. METHODS: A total of 1635 vocal cords were collected. The morphology were classified into three types (Type I, II, III): flat and smooth; bulge and smooth; bulge and rough. The pathological reports were classified into five groups: no dysplasia, mild dysplasia, moderate dysplasia, severe dysplasia and cancerization. The number of the patients or vocal cords in each type and group was counted and their ratio was compared. RESULTS: In Type I, the number of vocal cord in Group A group was 2.2 and 2.6 times of the one in Type II and Type III respectively. In Type II, the mild, moderate dysplasia ratio was higher than those in Type I. In Type III group the ratio of severe dysplasia was 2.6 and 5.5 times of the one in Type II and Type I respectively. The ratio of Group E in Type III was 2.7 and 7.9 times of the one of Type II and Type I. The result was significant (pearson Chi-square value was 517.6, p = .00). CONCLUSIONS: The pathological results of vocal cord leukoplakia can be evaluated by morphology in most cases.
BACKGROUND: To explore the relationship between the morphological characteristics and pathological diagnosis of vocal cords leukoplakia. METHODS: A total of 1635 vocal cords were collected. The morphology were classified into three types (Type I, II, III): flat and smooth; bulge and smooth; bulge and rough. The pathological reports were classified into five groups: no dysplasia, mild dysplasia, moderate dysplasia, severe dysplasia and cancerization. The number of the patients or vocal cords in each type and group was counted and their ratio was compared. RESULTS: In Type I, the number of vocal cord in Group A group was 2.2 and 2.6 times of the one in Type II and Type III respectively. In Type II, the mild, moderate dysplasia ratio was higher than those in Type I. In Type III group the ratio of severe dysplasia was 2.6 and 5.5 times of the one in Type II and Type I respectively. The ratio of Group E in Type III was 2.7 and 7.9 times of the one of Type II and Type I. The result was significant (pearson Chi-square value was 517.6, p = .00). CONCLUSIONS: The pathological results of vocal cord leukoplakia can be evaluated by morphology in most cases.