Literature DB >> 28707184

Misdiagnosis of tuberculosis associated with some species of nontuberculous mycobacteria by GeneXpert MTB/RIF assay.

Yu Pang1, Jie Lu2, Biyi Su3, Huiwen Zheng4, Yanlin Zhao5.   

Abstract

Out of 12 nontuberculous mycobacteria (NTM) species, 5 were identified as Mycobacterium tuberculosis (MTB) by GeneXpert at a bacterial load of 106. Notably, two species, including M. abscessus and M. smegmatis, were flagged as RIF-resistant MTB due to the high C(t) value of Probe E. In conclusion, our data have demonstrated that the misdiagnosis of MTB by GeneXpert assay is observed in five NTM species at a high bacterial load.

Entities:  

Keywords:  GeneXpert; Mycobacterium tuberculosis; Nontuberculous mycobacteria

Mesh：

Year:  2017        PMID： 28707184     DOI： 10.1007/s15010-017-1044-x

Source DB:  PubMed          Journal:  Infection        ISSN： 0300-8126            Impact factor:   3.553


  13 in total

1.  Novel polymorphic region of the rpoB gene containing Mycobacterium species-specific sequences and its use in identification of mycobacteria.

Authors:  Hyeyoung Lee; Hye-Eun Bang; Gill-Han Bai; Sang-Nae Cho
Journal:  J Clin Microbiol       Date:  2003-05       Impact factor: 5.948

2.  Bedaquiline in MDR/XDR-TB cases: first experience on compassionate use.

Authors:  Simon Tiberi; Saverio De Lorenzo; Rosella Centis; Pietro Viggiani; Lia D'Ambrosio; Giovanni Battista Migliori
Journal:  Eur Respir J       Date:  2013-08-29       Impact factor: 16.671

3.  Rapid molecular detection of extrapulmonary tuberculosis by the automated GeneXpert MTB/RIF system.

Authors:  Doris Hillemann; Sabine Rüsch-Gerdes; Catharina Boehme; Elvira Richter
Journal:  J Clin Microbiol       Date:  2011-01-26       Impact factor: 5.948

4.  Comparison of different drug susceptibility test methods to detect rifampin heteroresistance in Mycobacterium tuberculosis.

Authors:  Zhijian Zhang; Yufeng Wang; Yu Pang; Changting Liu
Journal:  Antimicrob Agents Chemother       Date:  2014-07-14       Impact factor: 5.191

5.  Diagnosis of tuberculosis and drug resistance: what can new tools bring us?

Authors:  F Drobniewski; V Nikolayevskyy; Y Balabanova; D Bang; D Papaventsis
Journal:  Int J Tuberc Lung Dis       Date:  2012-07       Impact factor: 2.373

6.  Differences in risk factors and drug susceptibility between Mycobacterium avium and Mycobacterium intracellulare lung diseases in China.

Authors:  Zhijian Zhang; Yu Pang; Yufeng Wang; Chad Cohen; Yanlin Zhao; Changting Liu
Journal:  Int J Antimicrob Agents       Date:  2015-03-01       Impact factor: 5.283

7.  Rapid molecular detection of tuberculosis and rifampin resistance.

Authors:  Catharina C Boehme; Pamela Nabeta; Doris Hillemann; Mark P Nicol; Shubhada Shenai; Fiorella Krapp; Jenny Allen; Rasim Tahirli; Robert Blakemore; Roxana Rustomjee; Ana Milovic; Martin Jones; Sean M O'Brien; David H Persing; Sabine Ruesch-Gerdes; Eduardo Gotuzzo; Camilla Rodrigues; David Alland; Mark D Perkins
Journal:  N Engl J Med       Date:  2010-09-01       Impact factor: 91.245

Review 8.  Infections caused by Mycobacterium abscessus: epidemiology, diagnostic tools and treatment.

Authors:  Faiza Mougari; Lorenzo Guglielmetti; Laurent Raskine; Isabelle Sermet-Gaudelus; Nicolas Veziris; Emmanuelle Cambau
Journal:  Expert Rev Anti Infect Ther       Date:  2016-10-03       Impact factor: 5.091

9.  Rapid detection of Mycobacterium tuberculosis and rifampin resistance by use of on-demand, near-patient technology.

Authors:  Danica Helb; Martin Jones; Elizabeth Story; Catharina Boehme; Ellen Wallace; Ken Ho; JoAnn Kop; Michelle R Owens; Richard Rodgers; Padmapriya Banada; Hassan Safi; Robert Blakemore; N T Ngoc Lan; Edward C Jones-López; Michael Levi; Michele Burday; Irene Ayakaka; Roy D Mugerwa; Bill McMillan; Emily Winn-Deen; Lee Christel; Peter Dailey; Mark D Perkins; David H Persing; David Alland
Journal:  J Clin Microbiol       Date:  2009-10-28       Impact factor: 5.948

10.  Determinants of PCR performance (Xpert MTB/RIF), including bacterial load and inhibition, for TB diagnosis using specimens from different body compartments.

Authors:  Grant Theron; Jonny Peter; Greg Calligaro; Richard Meldau; Colleen Hanrahan; Hoosain Khalfey; Brian Matinyenya; Tapuwa Muchinga; Liezel Smith; Shaheen Pandie; Laura Lenders; Vinod Patel; Bongani M Mayosi; Keertan Dheda
Journal:  Sci Rep       Date:  2014-07-11       Impact factor: 4.379
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